Prayer of Blessing. 🙏🏽❤. A prayer of blessing is one that calls on God's power to care for a person, place, thing or undertaking. Blessings in the Bible suggest an intimate relationship between the blesser and the blessed. A blessing from God marks an intimate relationship between God and man, serving as proof that he finds himself in God's favor. God, our loving Heavenly Father, wants us to communicate with Him through prayer. He always listens to us when we pray. Daily prayer can bless you,