miRNA genes are usually transcribed by RNA polymerase II (Pol II). [56] [57] The polymerase often binds to a promoter found near the DNA sequence, encoding what will become the …

In this review, we provide an update on canonical and non-canonical miRNA biogenesis pathways and various mechanisms underlying miRNA-mediated gene regulations. We also summarize …

MicroRNAs (miRNAs), widely distributed, small regulatory RNA genes, target both messenger RNA (mRNA) degradation and suppression of protein translation based on sequence …

2023年6月28日 · miRNAs are RNAs ~22 nucleotides in length that derive from longer primary miRNA (pri-miRNA) transcripts, which bear one or more hairpins (Fig. 1a). Most miRNA …

miRDB is an online database for miRNA target prediction and functional annotations. All the targets in miRDB were predicted by a bioinformatics tool, MirTarget, which was developed by …

MicroRNAs (miRNAs) are a class of small noncoding RNAs, which function in posttranscriptional regulation of gene expression. They are powerful regulators of various cellular activities …

2012年3月13日 · MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways. These small non-coding RNAs bind to target sequences in mRNAs, …

The miRNA gene undergoes a sophisticated processing cascade, involving RNA polymerase, the microprocessor complex, transporter proteins, and Dicer, culminating in the production of …

MicroRNAs (miRNAs) are a class of small (~19–24 nucleotides in length), endogenous, evolutionarily conserved RNAs that function as posttranscriptional regulators of gene expression.

MicroRNA （miRNA）是前几年的研究热点，其功能几乎覆盖了生命体的各个时期、各个过程，超过三分之一的基因都会受到miRNA调控。 miRNA可以通过调控其靶基因的进而影响蛋白表 …