Metabolic cage system for mouse, rat or larger animals. Suitable for calorimetry, behavioral and physiological studies. Multichannel implantable telemetry for In-vivo monitoring of physiological …

TSE strains are routinely identified by their incubation period and vacuolation profile in the brain after intracerebral inoculation and serial passaging in inbred mouse lines.

Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases that affect humans and animals. The hallmark lesion of TSEs is spongiform changes in the brains …

006234 B6.Cg-Tg (tetO-cre)1Jaw/J These transgenic mice express Cre recombinase under the control of a tetracycline-responsive promoter element (TRE or tetO) and are an effective tool …

However, after experimental transmission of a TSE to wild type or transgenic rodents a single or multiple phenotypes may emerge in a single mouse line, leading to the laboratory definition of …

Using gene targeted or knock out mice to understand the pathogenesis of TSE disease allows us to unravel the mechanisms of prion replication and the infective process whilst also providing a …

Metabolic cages (TSE Systems; photo) will be used in awake mice to simultaneously measure energy expenditure, physical activity, indirect calorimetry, and food/water intake.

2009年9月1日 · Groups of 16 mice were injected with the product after dilution to the equivalent of 1% concentration of the 301V brain spike and observed for signs of TSE disease. Surviving …

2014年9月9日 · TSE reference strains ME7, 87A/87V, 22A/22C, 79A/79V and 301C/301V were intracerebrally inoculated in RIII or VM inbred mice that differ in their PrP genotype. …

2003年6月1日 · Studies in mice have revealed considerable strain variation in the agents causing transmissible spongiform encephalopathies (TSEs). TSE strains interact with genetic factors in …