Threose is a four-carbon monosaccharide with molecular formula C 4 H 8 O 4. It has a terminal aldehyde group, rather than a ketone, in its linear chain and so is considered part of the aldose family of monosaccharides.

Erythro and threo are common terms in stereochemistry used for naming molecules with two stereogenic centers. The names derive from the saccharides erythrose and threose, so let’s draw their Fischer projection to understand the basis of this notation:

Threose nucleic acid (TNA) is an artificial genetic polymer in which the natural five-carbon ribose sugar found in RNA has been replaced by an unnatural four-carbon threose sugar. [1]

2024年2月1日 · Threose nuclei acid (TNA) stands out as a synthetic genetic polymer, holding potential as a primitive genetic material and as a contemporary molecular tool. In this review, we aim to provide an extensive overview of TNA research progress in these two key aspects.

In a pair of diastereomers, some of the chiral centers are the same in the two molecules, but others are different. Diastereomers are stereoisomers that are not mirror images of each other. Threose is an example of a biological molecule (a carbohydrate) that contains two chiral centers. Figure 5.9.1 5.9. 1: Pictures of D-threose.

The meaning of THREOSE is a syrupy synthetic sugar C4H8O4 that is the epimer of erythrose and that occurs as two optical isomers.

2022年11月11日 · Threose, like its diastereomer erythrose, exists as a rapidly converting equilibrium mixture of four species in an aqueous medium: the linear aldehyde, the corresponding hydrate, and the α- and β- cyclic hemiacetals (Scheme 3). 1-13 C Labeled threose was subjected to the identical reaction conditions at pH 8.5 as applied to 1-13 C-erythrose.

2024年10月15日 · This feature article delves into the realm of α-L-threose nucleic acid (TNA), an artificial nucleic acid analog characterized by a backbone comprising an unconventional four-carbon sugar, α-L-threose, with phosphodiester linkages connecting at the 2' and 3' vicinal positions of the sugar ring.

Threose is a four-carbon monosaccharide with molecular formula C 4 H 8 O 4. It has a terminal aldehyde group, rather than a ketone, in its linear chain and so is considered part of the aldose family of monosaccharides.

Threose, a metabolite of ascorbic acid, increases the AGE content of articular cartilage in vitro (34). Nutritional factors and osteoarthritis: a review article One called TNA replaces RNA's ribose sugar with a sugar called threose .