Thiophene is a heterocyclic compound with the formula C 4 H 4 S. Consisting of a planar five-membered ring, it is aromatic as indicated by its extensive substitution reactions. It is a colorless liquid with a benzene -like odor. In most of its reactions, it resembles benzene.

噻 sāi 吩 （吩咐的吩） （英語： Thiophene）是 杂环化合物， 化学式 C 4 H 4 S。 由平面五元环组成，其广泛的取代反应表明它有 芳香性。 它是无色液体，气味似 苯。 在其大部分反应中都类似苯。 噻吩最初是作为苯的杂质而发现的。 [1] 靛红 与硫酸、粗苯混合形成一种蓝色染料，早期认为这是苯的反应，直到德国化学家 维克托·梅耶 分离出噻吩，才发现了这种杂环化合物的存在。 [2] 噻吩天然存在于石油、煤焦油和页岩油中，在石油中含量可高达数个百分点，所以石油精炼中 …

噻吩（Thiophene），化学名称为1-硫杂-2,4-环戊二烯，是一种杂环化合物，也是一种硫醚。 分子式C4H4S。 在常温下，噻吩是一种无色、有恶臭、能催泪的液体。

Thiophene is a monocyclic heteroarene that is furan in which the oxygen atom is replaced by a sulfur. It has a role as a non-polar solvent. It is a mancude organic heteromonocyclic parent, a member of thiophenes, a monocyclic heteroarene and a volatile organic compound.

2025年3月24日 · 噻吩是含一个硫杂原子的五元杂环化合物，在煤焦油制得的粗苯中少量存在，具有类似苯芳香气味的无色液体，沸点为84℃，不溶于水，能与乙醇、乙醚、丙酮、苯、四氯化碳、庚烷、吡啶、1，4-二氧六环等混溶。 易燃。 耐热性强，加热至850℃而不分解。 在强酸条件下不聚合，不分解，也不易被氧化。 有中等程度毒性。 噻吩环上的5个原子均为sp2杂化，处于同一平面，硫原子的一对未共用电子占据的p轨道与4个碳原子的p轨道平行且重叠，形成5原子6电子 …

Thiophene is a privileged pharmacophore in medicinal chemistry owing to its diversified biological attributes. The thiophene moiety has been ranked 4th in the US FDA drug approval of small drug molecules, with around 7 drug approvals over the last decade. The present review covers USFDA-approved drugs possessing a thiophene ring system.

2024年7月24日 · Thiophene, a five-membered heterocyclic moiety containing one sulfur atom, possesses aromaticity. Among the sulfur-containing heterocyclic receptor systems, the synthesis of thiophene and its derivatives has drawn significant attention in the field of pharmaceutical chemistry for exhibiting a wide range of biological activities.

Thiophene, the simplest sulfur-containing aromatic compound, with molecular formula C4H4S, which closely resembles benzene in its chemical and physical properties. It occurs with benzene in coal tar, from which source it was first isolated in 1883.

用于制取合成药物（如噻乙吡啶、噻嘧啶及先锋霉素等）、染料、塑料等。 还可用作铀等金属的提取分离试剂。 有毒，有类似苯的强烈刺激性气味。 经皮肤吸收或吸入其蒸气均可引起中毒。 主要是刺激中枢神经，对血液毒性强度均为苯的1／5。 对家兔的皮下注射MLD 830mg/kg。 小白鼠吸入30mg/L，可在20～80 min内死亡。 生产过程中应注意设备密闭，防止泄漏。 应加强现场通风。 操作人员应穿戴防护用具，避免与人体直接接触。 工作场所空气中最大容许浓度0. 02mg/L。 本 …

2015年3月22日 · Thiophenes are a class of heterocyclic aromatic compounds based on a five-membered ring made up of one sulfur and four carbon atoms. The thiophene nucleus is well established as an interesting moiety, with numerous applications in a …