TRAF2 - Wikipedia
TRAF2 is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-κB. The protein complex formed by TRAF2 and TRAF1 interacts with the IAP family members cIAP1 and …
TNF 受体相关因子 2（TRAF2）基因 | MCE - MCE-生物活性 ...
TRAF proteins associate with, and mediate the signal transduction from members of the TNF Receptor Superfamily. This protein directly interacts with TNF receptors, and forms a …
肿瘤坏死因子受体相关因子(TRAF)信号传递新进展 - 每日生物评论
肿瘤坏死因子受体相关因子 (tumor necrosis factor receptor-associated factors, TRAF)是一类重要的具有多功能的细胞内信号转导因子。 TRAF参与多种受体家族的信号转导，包括肿瘤坏死因 …
TRAF2 Gene - GeneCards | TRAF2 Protein | TRAF2 Antibody
2024年12月25日 · TRAF2 (TNF Receptor Associated Factor 2) is a Protein Coding gene. Diseases associated with TRAF2 include Myeloma, Multiple and Hematologic Cancer. Among …
The TRAF2-p62 axis promotes proliferation and survival of
2023年4月20日 · TRAF2 depletion inhibited growth and survival of liver cancer cells both in vitro and in vivo by causing p62 accumulation, which is partially rescued by simultaneous p62 …
肿瘤坏死因子受体相关因子2 (TRAF2)在TNF信号传导中的作用
2015年7月22日 · TRADD ,RIP 和 TRAF2 ,参与凋亡和抗凋亡通路. 用,最终激活NF -κB 诱导基因表达和抗凋亡. 路,诱导细胞凋亡. 此外,可以依赖 TRAF2 寡聚抗. 碍激活凋亡通路 ( TRADD/ …
TNF Receptor Associated Factor 2 (TRAF2) Signaling in Cancer
Tumor necrosis factor (TNF) receptor associated factor-2 (TRAF2) is an intracellular adapter protein with E3 ligase activity, which interacts with a plethora of other signaling proteins, …
TRAF 蛋白结构域 | Cell Signaling Technology
人 TRAF 2 的单体 TRAF 结构域。 约有 150 个氨基酸的 TRAF 结构域可见于 肿瘤坏死因子 (TNF) 受体 相关 因子。 TRAF 蛋白似乎是一种相对最新进化的发育蛋白，因为只有一种 秀丽隐杆线 …
IF 12.067 ‖ 浙大医学院郑敏/赵永超团队揭示TRAF2调控肝癌增殖机 …
traf2作为衔接蛋白和泛素e3连接酶，在介导tnfα-nfκb信号通路中发挥重要作用，并在多种人类癌症中表达失调，但traf2是否调节肝癌细胞的生长尚不清楚。
Physiological Roles and Mechanisms of Signaling by TRAF2 and …
TRAF2 and TRAF5 therefore regulate diverse physiological roles, ranging from T and B cell signaling and inflammatory responses to organogenesis and cell survival. The major pathways …