意义未明的T细胞克隆性增殖（T-CUS）并不少见，大家需关注
2021年9月3日 · 下图是3个典型的大颗粒t淋巴细胞白血病（t-lgll）病例，用于与t-cus进行对比，其特点是在骨髓（上、下）或外周血（中）标本有类似的克隆性cd8阳性t细胞群（红色事件）， …
T-cell clones of uncertain significance are highly prevalent and …
2020年5月13日 · In routine laboratory practice, T-cell clones of uncertain significance (T-CUS) were detected in 42 of 159 (26%) patients without T-cell malignancy, and in 3 of 24 (13%) …
T-cell clones of uncertain significance are highly prevalent and …
TCR-Vβ repertoire analysis confirmed the clonality of T-CUS, and identified additional clonotypic CD8-positive subsets when combined with TRBC1 analysis. We hereby report the phenotypic …
T-cell clones of uncertain significance - ScienceDirect
2023年7月1日 · T-CUS shows immunophenotypic features closely resembling those of T-cell large granular lymphocytic leukaemia but the individuals are devoid of clinical or laboratory …
T-cell clones of uncertain significance. When is the rogue clone ...
2025年1月1日 · T-cell clones of uncertain significance (T-CUS) exhibit molecular and immunophenotypic features closely resembling those of T-cell large granular lymphocytic …
T-cell clones of uncertain significance in the era of increasingly ...
Results: T-CUS was identified in 152 samples from 92 patients. The majority (76%) were CD8+ and demonstrated an immunophenotype resembling large granular lymphocytes. Eighteen …
Monoclonal B-cell lymphocytosis, monoclonal gammopathy of …
2000年1月1日 · T-CUS are a potential precursor of T-cell malignancies, mainly T-cell large granular lymphocytic leukaemia. The precise incidence of T-CUS is still being refined. Due to …
T-cell clonality testing for the diagnosis of T-cell large granular ...
Benign clonal T-cell expansions, however, are commonly found in patients without identifiable disease, a condition referred to as T-cell clones of uncertain significance (T-CUS). In practice, …
Frontiers | Differential diagnosis and identification of prognostic ...
2022年11月17日 · We compared the differential expression of 15 markers in PTCL (Peripheral T-cell lymphoma) subtypes and T-CUS (T-cell clones of uncertain significance), and summarized …
Flow Cytometry Evaluation of T-Cell Receptor Constant Beta Chain …
2024年11月5日 · Here, we describe the occurrence of T-cell clones of uncertain significance (T-CUS) in peripheral blood, tissue, and body fluids in patients with no documented evidence of T …