2024年4月21日 · Subacute combined degeneration (SCD) of the spinal cord is a disease affecting the lateral and posterior columns of the spinal cord, primarily due to demyelination. It most commonly presents in patients deficient in vitamin B12, producing hematological and …

Subacute combined degeneration of spinal cord, also known as myelosis funiculus, or funicular myelosis, [1] also Lichtheim's disease, [2] [3] and Putnam-Dana syndrome, [4] refers to degeneration of the posterior and lateral columns of the spinal cord as a result of vitamin B 12 deficiency (most common).

2025年1月11日 · Subacute combined degeneration of the cord is caused by vitamin B 12 deficiency. Most common in patients older than 40 years and especially older than 60 years 7.

2024年3月20日 · Subacute combined degeneration is characterized by demyelination, resulting in degeneration of the spinal cord's dorsal and lateral columns. Common symptoms include sensory deficits, paresthesia, weakness, ataxia, and gait disturbance.

Subacute combined degeneration (SCD) is a disorder of the spine, brain, and nerves. It causes weakness , abnormal sensations , mental problems, and vision difficulties . The central nervous system comprises the brain and spinal cord.

Subacute combined degeneration refers to degenerative changes in the nervous system due to vitamin B12 deficiency; the degenerative changes affect mostly brain and spinal cord white matter. Demyelinating or axonal peripheral neuropathies can occur.

Subacute combined degeneration (SCD) is a disorder of the spine, brain, and nerves. It causes weakness, abnormal sensations, mental problems, and vision difficulties. SCD is caused by vitamin B12 deficiency. It mainly affects the spinal cord. But its effects on the brain and the peripheral (body) nerves are the reason for the term "combined."

In subacute combined degeneration, the myelin is damaged, causing sensory and motor nerve fibers from the spinal cord to degenerate. The brain, nerves of the eyes, and peripheral nerves are sometimes also damaged.

2024年4月21日 · Subacute combined degeneration (SCD) of the spinal cord is a disease affecting the lateral and posterior columns of the spinal cord, primarily due to demyelination. It most commonly presents in patients deficient in vitamin B12, producing hematological and …

Subacute combined degeneration (SCD), caused by vitamin B12 disorders, leads to severe degeneration of the spinal cord. Thus, it is significant to make timely diagnosis and treatment options of SCD. The objectives were to summarize clinical features of different sate SCD.