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In this study, we developed a DPZ ionic liquid (IL) transdermal patch—a novel transdermal preparation of DPZ that can overcome the current drawbacks. DPZ is an acetylcholinesterase inhibitor used to treat cognitive symptoms in mild to moderate AD [3,4,5]. In particular, it appears to benefit both cognitive ability and mental function [4,5 ...

Cholinergic deficit has been reported to be the major pathological cause for AD. In this case, the use of some acetylcholinesterase (AChE) inhibitors including galantamine, risvastigmine, and donepezil hydrochloride (DPZ) have been used to improve cholinergic function.

2024年8月13日 · The current study endeavors to design an in situ gel for intranasal delivery of a DPZ nanostructured lipid carrier (DPZ-NLC) to boost pharmacokinetic and pharmacodynamic outcomes. The Box–Behnken design was employed to optimize the NLCs that were produced utilizing a melt emulsification high-pressure homogenization process.

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2024年5月6日 · Find the perfect study DP for WhatsApp to showcase your dedication to learning and education. Discover a wide range of inspiring and motivational study-themed profile pictures to keep you motivated throughout your academic journey.

2023年10月10日 · Discover the perfect Student Study DP (Display Picture) collection to inspire your academic journey. Elevate your online presence with a variety of motivational, educational, and creative profile pictures tailored for students.

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