2025年1月28日 · MRI. T2/FLAIR: high signal within white matter in the parietal and temporal lobes in the acute stage 3. T1 C+ (Gd): enhancement of affected regions may occur early in the course of the disease. MR spectroscopy: may demonstrate 1,3. decreased NAA: from neuronal loss. increases in choline: from demyelination. increase myo-inositol: from active ...

2021年10月31日 · Subacute sclerosing panencephalitis (SSPE) is a slowly progressive neurodegenerative disease caused by the measles virus. This study investigated the magnetic resonance imaging (MRI) findings in SSPE by retrospective review of two cases diagnosed by typical periodic electroencephalographic (EEG) fea …

Subacute sclerosing panencephalitis, commonly known as SSPE, is a progressive neurodegenerative disease caused by the persistence of measles infection commonly seen in children and young adults. 1 SSPE was previously known as Dawson’s inclusion body encephalitis as Dawson in 1933 and 1934 reported cellular inclusions in the cerebral lesions ...

2020年8月18日 · We report six cases of SSPE with MRI findings mimicking metabolic disorder and leading to a diagnostic challenge, delay in referral and review. To gain a better insight into the importance of MRI findings, we comprehensively review the clinical, electroencephalographical and imaging features and highlight representative cases with emphasis on ...

2003年3月1日 · BACKGROUND AND PURPOSE: Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, inflammatory neurodegenerative disease. Our aim was to determine the metabolic abnormalities of brain in early- and late-stage SSPE by using MR spectroscopy and to assess areas of involvement in the early stages when MR imaging findings were normal.

2024年3月7日 · Our study found that WMH in the parieto-occipital region is a highly sensitive MRI indicator in patients diagnosed with SSPE who exhibit slow periodic myoclonus and falls. Furthermore, we observed a higher prevalence of diffuse cerebral atrophy in …

2017年1月1日 · Background and objectives: Subacute sclerosing panencephalitis (SSPE) is a progressive catastrophic neurodegenerative disease because of persistent measles viral infection in...

Subacute sclerosing panencephalitis (SSPE), first described by Dawson (1934), is chronic encephalitis due to persistent infection of the brain by an aberrant measles virus. Magnetic resonance imaging (MRI) is the most sensitive imaging modality in SSPE. Based on the previous reports, commonly involved areas are cerebral cortical ...

Subacute sclerosing panencephalitis (SSPE) is a progressive, slow virus infection of the brain, caused by the measles virus, attacking children and young adults. We investigated 15 patients with SSPE by MRI, with 5 normal and 10 pathological results.

Thirty-four MRI studies of 26 patients with subacute sclerosing panencephalitis are reported. Lesions of high signal intensity on T2-weighted images are the most common finding; they frequently involve the periventricular or subcortical white matter. Lesions tend to start in the cortex-subcortical w …