The SCOP database, created by manual inspection and abetted by a battery of automated methods, aims to provide a detailed and comprehensive description of the structural and evolutionary relationships between all proteins whose structure is known.

2021-09-20: SCOPe 2.08-stable has been released, with nearly 20,000 new pdb entries added since the last stable release. Important features include genetic variant search tools and annotations of structural heterogeneity and repeat units .

2024年6月25日 · The SCOP2 browser allows users to type in a protein name in the search box and select from the options in the autocomplete list. Alternatively, you can enter a SCOP2 unique identifier (SCOP ID) to find structure(s) of interest. Since there are two ways of classifying a protein - the protein name

SCOPe 2.08 data Starting with SCOPe version 2.01, data from all versions of SCOPe, SCOP, and Astral since 1.55 are stored in a relational database. To download a copy of the MySQL database released with stable SCOPe 2.08 (sql.bz2 format), click here (2 GB). Documentation for our schema is available here.

Structural Classification of Proteins — extended (SCOPe) is a database of protein structural relationships that extends the SCOP database. SCOP is a (mostly) manually curated ordering of domains from the majority of proteins of known structure in a hierarchy according to structural and evolutionary relationships.

2019年11月14日 · The SCOP version 2 builds on the advances in schema from the SCOP 2 prototype. To improve the database usability and facilitate the future updates, the SCOP 2 prototype design was simplified by reducing the levels of classification to: type , class , fold/IUPR , superfamily and family .

2021年4月23日 · The SCOP classification expanded to the represented structures (namely SCOP2B) and residue-level cross-reference between PDB and UniProtKB entries for SCOP domains are available from European Bioinformatics Institute FTP site that provides access to data from SIFTS.

Protein type groups folds and IUPRs into four groups: soluble, membrane, fibrous and intrinsically disordered. Each of these types to a large extent correlates with characteristic sequence and structural features. Each node in the SCOP classification can …

SCOP2 is a successor to the Structural Classification of Proteins (SCOP, http://scop.mrc-lmb.cam.ac.uk/scop/) database. Similarly to SCOP, the main focus of SCOP2 is to organize structurally characterized proteins according to their structural and evolutionary relationships.

The new Structural Classification of Proteins version 2 (SCOP2) database was released at the beginning of 2020. The new update featured an improved database schema, a new API and modernised web interface. This was the most significant update by the Cambridge group since SCOP 1.75 and builds on the advances in schema from the SCOP 2 prototype. [7]