2018年2月5日 · Single crystals of rufinamide grown in dimethylformamide (R-DMF) crystallized in triclinic form with P -1 space group. Solid state characterization of R-DMF were performed …

Two optimized and validated high performance liquid chromatography (HPLC) and spectrophotometric methods are proposed. The developed methods were quantified with high …

Rufinamide (R) is a triazole derivative approved for the management of partial seizures and seizures associated with Lennox-Gastaut Syndrome, in November 2007. Crystal structure, …

We have investigated the solid dispersion and dissolution profiles of three antiepileptic drugs (carbamazepine (CBZ), oxcarbazepine (OXC) and rufinamide (RFN)) with different aqueous …

2020年7月26日 · Rufinamide is a triazole derivative that is structurally dissimilar to other marketed antiepileptic drugs, has been assumed a marketing authorization, by the European Union and …

Rufinamide provides an efficacious and well-tolerated treatment option for use as adjunctive therapy in patients with partial seizures and with Lennox-Gastaut syndrome (LGS). In LGS, …

2013年1月1日 · Rufinamide is a new, orally active antiepileptic drug (AED), which has been found to be effective in the treatment of partial seizures and drop attacks associated with the Lennox …

In late 2008, the Food and Drug Administration approved rufinamide for adjunctive use in the treatment of seizures associated with Lennox–Gastaut syndrome. This unique chemical …

2018年2月5日 · Single crystals of rufinamide grown in dimethylformamide (R-DMF) crystallized in triclinic form with P -1 space group. Solid state characterization of R-DMF were performed …

2018年12月1日 · Rufinamide (RUFI), an antiepileptic drug (AED) [1- (2,6-difluoro-phenyl) methyl-1H-1,2,3-triazole-4-carboxamide] is a triazole derivative, structurally unrelated to other AEDs. …