2013年11月1日 · Rotational-echo double-resonance (REDOR) NMR is a powerful and versatile solid-state NMR measurement that has been recruited to elucidate drug modes of action and to drive the design of new therapeutics.

2020年8月16日 · Rotational-echo, double-resonance (REDOR) NMR is a high-resolution, solid-state NMR experiment for measuring the dipolar coupling between a heteronuclear spin pair [1,2]. The 1/r3 distance dependence of the dipolar coupling makes REDOR useful for the structural...

Rotational-echo double resonance (REDOR) is an ss-NMR methodology, which by reintroducing heteronuclear dipolar coupling under magic angle spinning conditions provides intramolecular and intermolecular distance restraints at the atomic level. In addition, REDOR can be exploited as a selection tool to filter spectra based on dipolar couplings.

Rotational-echo, double-resonance (REDOR) NMR is a high-resolution, solid-state NMR experiment for measur-ing the dipolar coupling between a heteronuclear spin pair 1/r3 [1,2].

A 1H–13C frequency-selective REDOR (FS-REDOR) experiment is developed for measuring intramole- cular 1 H– 13 C distances in uniformly 13 C, 15 N-labeled molecules. Theory and simulations show that the

2003年2月5日 · REDOR is a high resolution solid NMR experiment employing magic angle spinning and cross polarization to measure the distance between two select labeled heteronuclei, such as C13 - N15. C13-O17 in the molecule.

2025年2月17日 · The Resonance Echo DOuble Resonance (REDOR) experiment is an effective means of probing through-space internuclear distances between nuclei. It is limited to systems where both nuclei are spin-1/2, or where one nucleus is spin-1/2 and the other is a half-integer-spin quadrupole where you can obtain good spectra via magic angle spinning (e.g ...

2018年1月2日 · REDOR NMR detects multiple conformations for a bryostatin analogue complexed with a PKCδ-C1b domain in functionally relevant phospholipid vesicles, thereby establishing a platform to evaluate other ligands and effects on PKC function.

2019年11月1日 · Rotational-echo double resonance (REDOR) and Dipolar-coupling chemical-shift correlation (DIPSHIFT) are commonly used experiments to probe heteronuclear dipole-dipole couplings between isolated pairs of spin-1 2 nuclei in magic-angle-spinning (MAS) solid-state NMR. Their widespread use is due to their robustness to experimental imperfections ...

2009年1月1日 · REDOR has been implemented to examine composition, structure, and dynamics in diverse macromolecular and whole-cell systems, including taxol-bound microtubules, enzyme–cofactor–inhibitor ternary complexes, and antibiotic–whole-cell complexes.