Whole brain radiotherapy (WBRT) is a treatment option for patients with brain metastases. In WBRT, radiation therapy is administered broadly, to the whole brain, over multiple treatments. [1]

1． WBRT： WBRT 是脑转移瘤的主要局部治疗手段之一，可以缓解肺癌脑转移患者的神经系统症状、改善肿瘤局部控制情况。 WBRT 对颅内亚临床病灶有一定的控制作用，但因其受正常脑组织的剂量限制，难以…

Whole-brain radiation therapy (WBRT) is a treatment modality that has been used since the 1950s for patients with brain metastases (14). It is commonly delivered to a total dose of 30 Gy over 10 sessions. Clinicians traditionally favored WBRT due to its efficacy in providing palliation and ability to target unknown microscopic intracranial disease.

2023年10月6日 · 全脑放疗(wbrt)是脑转移最为基础的放疗方式。对于多发脑转移患者(通常指病灶数＞3)，wbrt可以使中位生存期延长至3～6个月，并有10%～15%的患者生存时间超过1年。wbrt使约60%颅内肿瘤退缩，并改善了患者的神经系统症状及预后。 wbrt最常用的分割形式为30gy/10f。

Whole brain radiotherapy (WBRT) is a mainstay of treatment in patients with both identifiable brain metastases and prophylaxis for microscopic disease. The use of WBRT has decreased somewhat in recent years due to both advances in radiation ...

2017年6月18日 · Hippocampal avoidance WBRT. Axial slices are presented from caudal (a) to cranial (d) extent with CT and matched T1 series MRI. Structures highlighted include the hippocampal formation of interest (red), expansion (blue), normal brain tissue (khaki), and brain stem (black). The CTV contains all normal brain tissue with the hippocampal formation ...

2021年4月7日 · Treatment options for brain metastases include whole brain radiation therapy (WBRT), stereotactic radiosurgery (SRS), surgery, and systemic therapies. These treatment options may be considered alone or in combination. For some patients, palliative care alone may be …

Radiotherapy is one of the most important treatments for metastatic brain cancer. The purpose of this study was to assess whether whole brain radiation therapy (WBRT) with simultaneous integrated boost (SIB) provided any therapeutic benefit relative to WBRT followed by stereotactic radiosurgery (SRS).

2018年11月1日 · There has been no definitive regimens on how to integrate whole brain radiotherapy (WBRT) and local boost for brain metastatas (BMs). To compare the therapeutic effect and cerebral cognitive dysfunction in non-small cell lung cancer patients with finite number of BMs (≤10) treated by WBRT plus sequential integrated boost (SEB) or simultaneous ...

2010年11月1日 · Because of the superior dosimetry of this technique compared to WBRT with conventional stereotactic radiosurgery, we have adopted this approach as standard treatment in pts with multiple BM and pts who received postoperative WBRT with a boost to residual BM. We report on the clinical outcomes in a cohort of pts treated with WBRT+SIB.