2023年2月15日 · RNA ligases play vital roles in sealing RNA strands during intron-containing tRNA splicing 1, tRNA repair 2, mRNA splicing in the unfolded-protein response (UPR) 3, RNA …

2004年2月27日 · In the current issue of Structure, Ho and coworkers report the crystal structure and mechanism of a T4 RNA ligase. These studies provide valuable insights on the …

RNA Ligase is an enzyme that plays a crucial role in the synthesis of long RNA molecules by joining RNA junctions in double-stranded regions efficiently and selectively.

View a chart of NEB's DNA and RNA ligases, their differences, and recommendations for optimal performance.

Phage T4 polynucleotide kinase/phosphatase (Pnkp) and RNA ligase 1 (Rnl1) are prototypal RNA healing and sealing enzymes. They function in vivo to repair a break in E. coli tRNA Lys …

RNA ligation is a process that can be achieved with various intermediaries such as self-catalysing RNAs, 5′–3′ and 3′–5′ RNA ligases. While several types of RNA ligation mechanisms occur in …

We report the 1.9 A crystal structure of the ligase domain with AMP bound at the active site, which reveals a shared fold, catalytic mechanism, and evolutionary history for RNA ligases, DNA …

We report the 1.9 Å crystal structure of the ligase domain with AMP bound at the active site, which reveals a shared fold, catalytic mechanism, and evolutionary history for RNA ligases, DNA …

In enzymology, an RNA ligase (ATP) (EC 6.5.1.3) is an enzyme that catalyzes the chemical reaction ATP + (ribonucleotide)n + (ribonucleotide)m AMP + diphosphate + (ribonucleotide)n+m.

2014年3月28日 · Isolation and characterization of a thermostable RNA ligase 1 from a bacteriophage TS2126 with good single-stranded DNA ligation properties