Pyruvic acid (CH 3 COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group. Pyruvate, the conjugate base, CH 3 COCOO −, is an intermediate in several metabolic pathways throughout the cell.

Pyruvate is a three-carbon acid that is naturally formed during glycolysis, the process in which the body breaks down sugar (glucose). Pyruvate might increase the breakdown of fat, which could...

2019年4月8日 · Pyruvate is an important molecule that is present at the intersection of multiple biochemical pathways. It is commonly encountered as one of the end products of glycolysis, which is then transported to the mitochondria for participating the citric acid cycle.

Pyruvate is a 2-oxo monocarboxylic acid anion that is the conjugate base of pyruvic acid, arising from deprotonation of the carboxy group. It has a role as a fundamental metabolite and a cofactor.

Pyruvate is the master carbon fuel input supporting overall citric acid cycle carbon flux. Pyruvate transits the inner mitochondrial membrane (IMM) through the mitochondrial pyruvate carrier (MPC) to reach the mitochondrial matrix.

2023年6月1日 · Pyruvate is the end product of glycolysis, which is converted into acetyl coA that enters the Krebs cycle when there is sufficient oxygen available. But when the oxygen is insufficient, pyruvate is broken down anaerobically, such as in fermentation that creates lactate or ethanol as an end-product.

What is Pyruvic acid? It is the simplest ɑ-keto acid that has carboxylic acid and ketone as its functional group. When pyruvic acid donates a proton, it forms a conjugate base called pyruvate. Pyruvate is seen as an intermediate in most metabolic …

Pyruvic acid, an organic acid that probably occurs in all living cells. It ionizes to give a hydrogen ion and an anion, termed pyruvate. It is a key product at the crossroads between the catabolism (breaking down) and anabolism (synthesizing) of carbohydrates, fats, and proteins.

2024年10月17日 · Pyruvate is a pivotal molecule in cellular metabolism and energy production, acting as an intermediary that bridges various metabolic pathways. Its role extends beyond being just an end product of glycolysis; pyruvate serves as a substrate for further biochemical processes essential for life.

2019年5月30日 · Pyruvate is an intermediate compound in the metabolism of fats, proteins, and carbohydrates. It can be formed from glucose via glycolysis or the transamination of alanine. It can be converted into Acetyl-CoA to be used as the primary energy source for the TCA cycle, or converted into oxaloacetate to replenish TCA cycle intermediates.