2017年6月1日 · The activation properties of PIFA as an excellent activator of alkynes moiety has prompted us to hypothesize that the ynamide bearing 3,4-dimethoxyphenylethane and tert-butyloxy carbamate moieties on the nitrogen atom could react with PIFA in the presence of Lewis acid via cycloisomerization to form a new C O bond (Scheme 1 d).

Direct Arylation of Oligonaphthalenes Using PIFA/BF3·Et2O: From Double Arylation to Larger Oligoarene Products. The Journal of Organic Chemistry 2013 , 78 (16) , 8169-8175.

2013年7月16日 · Direct dehydrogenative coupling between the linear ter- and quaternaphthalenes and substituted benzenes was achieved under the Kita conditions using the hypervalent PIFA/BF 3 reagent. Products resulting from either the double arylation of the naphthalenic substrate or the formal dimerizative arylation have been prepared.

2010年12月29日 · 该方法可扩展到未官能化的 1,1'-联萘与均三甲苯的偶联，以显着的化学选择性方式以 87% 的产率得到线性六芳烃产物。 该方法代表了通过一系列金属催化交叉偶联步骤合成相关低聚萘产品的一种有吸引力的替代方法。 发现萘和取代苯之间的直接氧化 Kita 型偶联是通过四组分偶联进行的，导致具有联萘核的线性四芳烃。 该方法可扩展到未官能化的 1,1'-联萘与均三甲苯的偶联，以显着的化学选择性方式以 87% 的产率得到线性六芳烃产物。 该方法代表了通过一 …

2024年7月2日 · In this study, we present our findings on the synthesis of α-, β-, γ-carbolines via PIFA/BF 3 ·OEt 2-mediated intramolecular cyclization of isomeric azidomethyl(indolyl)acrylates. Alternately, 1,5,7-triazabicyclo[4.4.0]dec-5-ene/1,8-diazabicyclo(5.4.0)undec-7-ene (TBD/DBU)-mediated Michael addition followed by intramolecular cyclization of ...

2010年12月29日 · Direct oxidative Kita-type coupling between naphthalene and substituted benzenes was found to proceed via four-component coupling, leading to a linear tetraarene with a binaphthalene core. The methodology was extendable to the coupling of unfunctionalized 1,1'-binaphthalene with mesitylene to give a …

A simple and efficient method has been developed for the switchable synthesis of directly linked meso-brominated Ni(ii) porphyrin dimers through PIFA–BF3·Et2O mediated oxidative coupling. The respective syntheses of meso–meso or meso–β singly, doubly, and triply linked porphyrin dimers can be easily realized

2017年6月1日 · PIFA-Mediated Tandem Hofmann-Type Rearrangement and Cyclization Reaction of α-Acyl-β-aminoacrylamides: Access to Polysubstituted Oxazol-2 (3H)-ones. An efficient and straightforward synthesis of polysubstituted oxazol-2 (3H)-ones has been developed via a tandem Hofmann-type rearrangement and cyclization reaction of various…

2017年6月1日 · An efficient and straightforward synthesis of polysubstituted oxazol-2­(3H)-ones has been developed via a tandem Hofmann-type rearrangement and cyclization reaction of various α-acyl-β-aminoacrylamides mediated by phenyl iodine­(III) bis­(trifluoroacetate) (PIFA) in the presence of trifloroacetic acid (TFA). This novel protocol features ...

2017年6月1日 · PIFA-BF 3 ·OEt 2 mediated intramolecular regioselective domino cyclization of ynamides: A novel method for the synthesis of tetrahydroisoquinoline-oxazol-2(3H)-ones Bioorg Med Chem . 2017 Jun 1;25(11):2856-2867. doi: 10.1016/j.bmc.2017.03.034.