Piezo1 channels were relatively insensitive to mechanical stimuli pushing the cell membrane, whereas forces pulling the membrane could activate the channel effectively.

2025年3月30日 · Complete information for PIEZO1 gene (Protein Coding), Piezo Type Mechanosensitive Ion Channel Component 1 (Er Blood Group), including: function, proteins, …

Piezo1, a mechanosensitive ion channel, has emerged as a key player in translating mechanical stimuli into biological signaling. Its involvement extends beyond physiological and pathological …

2024年10月25日 · Piezo1, a newly identified mechanosensitive protein located on the cell membrane, is capable of transducing mechanical signals into biological responses. 6, 7 The …

2024年7月5日 · Piezo1 is a key mechanotransducer in various organ systems throughout the human body. It can sense mechanical forces and convert them into electrochemical responses …

2019年10月3日 · Mechanosensitive Piezo1 and Piezo2 channels transduce various forms of mechanical forces into cellular signals that play vital roles in many important biological …

2022年5月12日 · Piezo1 is a member of the mechanosensitive piezo ion channel family, which transduces various mechanical stimulations into electrochemical signals. Piezo1 is closely …

2025年4月1日 · Additionally, we observed activated Piezo1 and HK2-mediated glycolysis in patients with temporomandibular joint OA, thereby confirming the clinical relevance of our …

6 天之前 · Piezo1 deletion in vascular smooth muscle cells protects Piezo1 del/lox Cre mice against hypoxia-induced endothelial cell senescence and microvascular rarefaction. A, …

2021年10月20日 · In this review, we emphasize the diverse functions of Piezo1 and Piezo2 and related signaling pathways in osteoblast lineage cells and chondrocytes. We also summarize …