As markers for monocyte activation, differentiation, and induction of an innate immune response, expression of CD11b, TLR2, TLR4, and CD36 on THP1 cells was measured by flow (Fig. 1B), …

2022年5月25日 · To determine whether THP-1 macrophages have larger amounts of LPS-related-receptors and intracellular proteins, CD14 and TLR4 were characterized by flow cytometry in …

In this study, we found that pro-inflammatory cytokines-IL-1β, IL-6 and TNFα showed greater induction in phorbol-12-myristate-13-acetate (PMA)-differentiated THP-1 cells than in THP-1 …

2021年3月24日 · In vitro results show SYQP activated HEK-BLUE hTLR4 instead of HEK-BLUE Null cells. The secretion and the mRNA expression of cytokines related to TLR4 signaling …

2017年12月12日 · We found that THP1-derived macrophages or PMA primed THP-1 macrophages exhibit higher surface TLR4 levels and increased NOX2 expression levels …

(A) Expression of TLR2 and TLR4 in PMA-activated THP-1 cells was analyzed by RT-PCR. Total RNA was isolated from PMA-activated THP-1 cells cultured in medium with or without HK Y or …

Neoseptins, chemically synthesized peptidomimetics that bind and activate the mouse TLR4 (mTLR4)/MD-2 complex independent of LPS, were discovered through unbiased screening …

2016年10月10日 · Curcumin also markedly inhibited the upregulation of toll-like receptor 4 (TLR4), myeloid differentiation factor 88 (MyD88), phosphorylation level of IκB-α, and …

1.pma诱导hl-60细胞分化过程中tlr2和tlr4以及cd14的表达动力学研究;2.小鼠巨噬细胞热休克反应通过iκbα/nf-κb信号通路抑制lps诱导的白细胞介素12表达 来自 知网

2015年2月24日 · Our findings suggest that O. japonicus could elicit inflammatory reactions in PMA-activated THP-1 cells and contribute to inflammatory processes, a process mediated by …