Polypoidal choroidal vasculopathy (PCV) is a disease of the choroidal vasculature. It is present in both men and woman of many ethnicities, characterized by serosanguineous detachments of the pigmented epithelium and exudative changes that can commonly lead to subretinal fibrosis.

2012年12月1日 · Diagnosis: Choose ICG. Regardless of genetics, PCV has a distinctive appearance, particularly on indocyanine green (ICG) angiography, which is currently the best technique for differentiating it from other forms of neovascularization.

Polypoidal choroidal vasculopathy (PCV) is a vascular disease of the choroid that leads to hemorrhagic and exudative macular degeneration. It may cause significant vision loss and thus affect the quality-of-life and psychological well-being.

2014年5月4日 · On fundus examination, the most suggestive findings of PCV are orange-red subretinal nodules, spontaneous SRH, and either serous or hemorrhagic PED. The presence of one or more of these features suggest a diagnosis of PCV, and ICG should be performed.

How to define “Polyp” and “Abnormal Vascular Network” on ICGA? Which phases of ICGA are critical for diagnosing PCV? Typically, the early phase of the ICG angiogram (First 1 min) reveals a distinct network of vessels within the choroid, called as abnormal vascular network (AVN).

The most important test used to diagnose PCV is a careful dilated eye examination by your retina specialist. In addition, fluorescein and indocyanine green (ICG) angiography may be useful (Figure 2). These 2 tests are able to create detailed images of the retinal and choroidal blood vessels, which can assist your retina specialist in ...

This report presents the APOIS PCV Workgroup updated nomenclature of PCV based on our current understanding of PCV using new clinical, imaging, and histopathologic data. We recommend a set of diagnostic criteria for PCV without the need for ICGA that can achieve high sensitivity, specificity, and an AUC when compared with ICGA as the gold standard.

The Everest study has further described the imaging standards and grading protocol of PCV. 85 PCV is diagnosed based on early subretinal ICGA hyperfluorescence (appearing within the first 5 min of ICG dye injection) and at least one of the following diagnostic criteria:

2025年3月12日 · However, non-ICG multimodal PCV analysis using more standard imaging techniques has become more commonly used due to variable availability of ICG angiography at clinical sites and studies have validated and support the accuracy of this approach. 9, 10, 39, 40 This study also only considered combination with ranibizumab anti-VEGF-A therapy, and ...

Indocyanine green (ICG) angiography was instrumental in confirming the diagnosis of polypoidal choroidal vasculopathy (PCV). This is an important observation in that proper differentiation may have an impact on treatment and management decisions in these patients.