2024年12月23日 · Here, we showed that Arabidopsis thaliana OXIDATIVE SIGNAL-INDUCIBLE1 (OXI1), a kinase known to be activated by ROS, is involved in the LYK5-CERK1 receptor complex, which recognizes fungal cell wall-derived chitin. The oxi1 mutant exhibits enhanced susceptibility to various pathogens and reduced chitin-induced MAPK activation and ROS burst.

2022年11月1日 · OXI1 contributes to enhanced immunity by induced SA biosynthesis via CBP60g-induced expression of SID2 and camalexin accumulation via WRKY33-targeted transcription of PAD3. OXI1 regulates genes involved in reactive oxygen species (ROS) generation such as RbohD and RbohF.

2024年11月20日 · Here, we showed that Arabidopsis thaliana OXIDATIVE SIGNAL-INDUCIBLE1 (OXI1), a kinase known to be activated by ROS, is involved in the LYK5–CERK1 receptor complex, which recognizes fungal cell wall–derived chitin. The oxi1 mutant exhibits enhanced susceptibility to various pathogens and reduced chitin-induced MAPK activation and ROS burst ...

2024年11月21日 · OXI1激酶被活性氧（ROS）激活，参与调控MAPK级联和ROS爆发。 研究显示，OXI1突变体对病原体的敏感性增加，且几丁质诱导的MAPK活化和ROS爆发减少。 此外，OXI1通过磷酸化MAPKKK5和RbohD，进一步调节MAPK活化和ROS产生，揭示了PRR介导的ROS产生与MAPK激活之间的分子机制。 本站注明稿件来源为其他媒体的文/图等稿件均为转载稿，本站转载出于非商业性的教育和科研之目的，并不意味着赞同其观点或证实其内容的真实性 …

OXI1 contributes to enhanced immunity by induced SA biosynthesis via CBP60g-induced expression of SID2 and camalexin accumulation via WRKY33-targeted transcription of PAD3. OXI1 regulates genes involved in reactive oxygen species (ROS) generation such as …

oxi1 突变体表现出对各种病原体的敏感性增强，并减少几丁质诱导的 MAPK 激活和 ROS 爆发。 我们发现几丁质以 RbohD 依赖性方式诱导 OXI1 的磷酸化。 H 2 O 2 和几丁质处理导致 OXI1 在 Cys104 和 Cys205 位点氧化，这对 OXI1 的激酶活性至关重要。

2024年12月4日 · Co-immunoprecipitation assays revealed that activated OXI1 directly interacts with MAPKKK5 and RbohD, which it phosphorylates in response to chitin perception. This suggests that OXI1 engages in a positive feedback loop during PTI, as RbohD phosphorylation has been linked to increased ROS generation.

The results suggest that resistance in oxi1-2 mutants is through induction of callose deposition via MAPKs resulting in ROS induction as an early response. Furthermore, the results suggest that the β-1,3-glucanase genes, especially GNS2, play an …

2024年11月26日 · 该研究发现一个已知受到ROS信号激活的蛋白激酶OXI1与LYK5、CERK1互作，是植物免疫受体复合体新组分。在oxi1突变体中，chitin诱导的MAPK激活和ROS爆发比野生型降低。

使用转录组学、蛋白质组学和代谢组学分析，我们提供证据表明OXI1是光合作用的负调节因子，但正调节关键防御因子、ROS 和 camalexin 的生物合成。 重要的是，我们表明 OXI1 调节 NHP 和 SA（SAR 的两个关键调节剂）生物合成的各个步骤。