Here, we present a comparative analysis of human, chicken, and worm genes leading to the identification of 25 “orphan” retrogenes, which likely replaced their progenitors, in the human …

In medicine, orphan genes represent a rich yet relatively unexplored resource that holds promise for understanding human health and addressing disease. These genes, which lack detectable …

An orphan is a child whose parents have died, are unknown, or have permanently abandoned them. It can also refer to a child who has lost only one parent, as the Hebrew translation, for …

A series of liquid chromatography/mass spectrometry/informatics approaches are discussed, along with some successes with both human and bacterial P450s. Current information on what …

2011年8月31日 · Orphan genes might arise from duplication and rearrangement processes followed by fast divergence; however, de novo evolution out of non-coding genomic regions is …

Orphan Genes (OGs) are a mysterious class of genes that have recently gained significant attention. Despite lacking a clear evolutionary history, they are found in nearly all living …

ORFanID is a web-based software engine that identifies ORFan genes from the genomes of specified species or from a given list of DNA sequences. The scope of the search for orphan …

2012年10月12日 · We performed a comparative analysis of human, chicken, and worm genomes to identify “orphan” retrogenes, that is, retrogenes that have replaced their progenitors. We …

Northern blotting indicated a specific expression to the brain, primarily in neurons of the hippocampus, cerebellum, and cortex. Full-length human P450 4X1 cDNA was cloned using …

2014年6月1日 · There exist reports with strongly indicative evidence for de novo gene emergence in many organisms ranging from Bacteria, sometimes generated through bacteriophages, to …