Nicorandil is a vasodilator drug used to treat angina, which is chest pain that results from episodes of transient myocardial ischemia. Angina can be caused by diseases such as atherosclerosis , coronary artery disease , and aortic stenosis .

Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of cyclic GMP. It is shown to dilate normal and stenotic coronary arteries and reduces both ventricular preload and afterload 10.

Nicorandil is a safe, well-known antianginal agent that has been approved as a long-term therapy for chronic stable angina in Japan and Europe.

Find out how nicorandil treats chest pain (angina), and how to take it. NHS medicines information on nicorandil – what it's used for, side effects, dosage and who can take it.

Nicorandil is used in the treatment of Hypertension (high blood pressure), Angina (heart-related chest pain), Heart Failure. View Nicorandil’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com.

2024年12月16日 · Nicorandil works by relaxing (widening) your blood vessels. This increases the supply of blood and oxygen to your heart and helps to reduce the number of angina attacks you have. It can also reduce the risk of further heart conditions.

2025年1月7日 · Nicorandil dilates arterioles and large coronary arteries by opening the potassium channels, and stimulates guanylate cyclase causing venous vasodilatation. It therefore reduces preload and afterload, and improves coronary blood flow.

Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of cyclic GMP. It is shown to dilate normal and stenotic coronary arteries and reduces both ventricular preload and afterload.

View nicorandil information, including dose, uses, side-effects, pregnancy, breast feeding and contra-indications.

Nicorandil is a medicine used to treat and reduce chest pain caused by angina. It works by relaxing and widening your blood vessels and increasing the blood and oxygen supply to your heart. Your doctor will usually prescribe nicorandil when other heart medicines have not worked or are not suitable for you.