ABSTRACT: Antiphospholipid syndrome (APS) is an autoimmune disorder defined by the presence of characteristic clinical features and specified levels of circulating antiphospholipid antibodies Box 1 and Box 2. Diagnosis requires that at least one clinical and one laboratory criterion are met.

Cases with incomplete clinical or laboratory data are classified as obstetric morbidity APS (OMAPS) and non-criteria OAPS (NC-OAPS), respectively. Inflammatory and thrombotic mechanisms are involved in the pathophysiology of OAPS. Trophoblasts, endothelium, platelets and innate immune cells are key cellular players.

Antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy complications in the presence of persistent antiphospholipid antibodies (APLA).

Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by thrombotic episodes in the arterial or venous circulation, in the presence of antiphospholipid antibodies (aPL), namely lupus anticoagulant (LA), anticardiolipin antibodies, and anti-β2glycoprotein-I antibodies (anti-β2GPI) (1).

2000年9月1日 · Antiphospholipid antibodies (APAs) are a diverse group of autoantibodies (immunoglobulins) with different target self-antigens, among which are negatively charged phospholipids or phospholipid-containing structures of plasma cell …

2025年1月23日 · Below, they answered the three most commonly asked questions about APAS: Is it possible to have APAS even if you already have a child whom you conceived without being diagnosed with APAS? Yes, it is possible. APAS is an acquired condition, and you can have it in your next pregnancies.

2016年8月9日 · APAS raises the risk for miscarriages, stillbirths, premature delivery and preeclampsia (high blood pressure during pregnancy). When preeclampsia progresses, it leads to eclempsia which is a serious condition that causes seizures in pregnant women.

2018年10月20日 · Antiphospholipid Antibody Syndrome (APAS), is an autoimmune condition. It’s also called “Hughes’ Syndrome,” after Graham Hughes who led the team that discovered it in 1983. An autoimmune condition is when the immune system, which normally helps the body fight diseases and infections, instead attacks healthy cells and tissues.

In this study, we evaluated the feasible timing after discontinuation of APAs. Methods and results: Sixty-two patients taking APAs, who were scheduled to undergo elective NCP, were enrolled. All patients took either aspirin 100 mg or aspirin 100 mg plus clopidogrel 75 mg daily.

2018年5月24日 · The antiphospholipid syndrome is a systemic autoimmune disease defined by thrombotic or obstetrical events that occur in patients with persistent antiphospholipid antibodies....