Myostatin (also known as growth differentiation factor 8, abbreviated GDF8) is a protein that in humans is encoded by the MSTN gene. [6] Myostatin is a myokine that is produced and …

2022年12月15日 · Myostatin is a human growth factor that prevents excessive muscle growth, and abnormally high levels can cause the loss of muscle mass. Despite the lack of proper …

Myostatin (MSTN) is a well-reported negative regulator of muscle growth and a member of the transforming growth factor (TGF) family. MSTN has important functions in skeletal muscle …

2014年4月10日 · Myostatin is a highly druggable protein because it is secreted and accessible in the circulation. Researchers are investigating the use of antibodies, propeptides, interacting …

Myostatin, also known as growth differentiation factor 8 (GDF8), is a transforming growth factor-β (TGF-β) family member that potently inhibits skeletal muscle development [1].

Myostatin (GDF-8) was discovered 25 years ago as a new transforming growth factor-β family member that acts as a master regulator of skeletal muscle mass. Myostatin is made by …

Myostatin is a secreted protein that negatively regulates skeletal muscle mass determining both muscle fiber number and size. The myostatin pathway is conserved and regulates muscle …

In this chapter, we review myostatin biology, including intracellular and extracellular regulatory pathways, and the role of myostatin in modulating physiologic processes, such as muscle …

2022年1月1日 · Myostatin is a member of the transforming growth factor (TGF)-β superfamily. It is expressed by animal and human skeletal muscle cells where it limits muscle growth and …

2022年11月18日 · Myostatin-related muscle hypertrophy is a rare genetic condition that causes a person to grow significantly more muscle mass than what is considered normal. It also causes …