Whole-body cellular mapping in mouse using standard IgG antibodies …
2023年7月10日 · We introduce wildDISCO, a new approach for whole-body immunolabeling, optical clearing and imaging in mice, circumventing the need for transgenic reporter animals or …
The mouse that roared for human advantage - Nature
New mouse models that express fully human antibodies without diminished immune response could speed the development of therapeutic leads. Credit: Getty Images. In 2017, the number …
Mouse Antibody - labome.com
2022年11月20日 · As of June 5, 2022, Labome antibody database lists 106246 monoclonal antibodies against 8684 mouse genes, and 100849 polyclonal antibodies against 13590 …
Design and characterization of mouse IgG1 and IgG2a bispecific ...
In the field of bispecific antibodies, there remains a dearth of technologies available to generate native IgG-like mouse bispecific antibodies. Thus, we engineered a simple co-expression …
A toolbox of anti–mouse and anti–rabbit IgG secondary nanobodies
Mouse and rabbit antibodies are fundamental tools for numerous basic research techniques and medical diagnostic assays. The detection or immobilization of these primary antibodies is most …
Background-free Detection of Mouse Antibodies on Mouse …
Mouse isotype-specific antibodies, differently from reagents directed against both heavy and light chains, fail to detect endogenous Ig after fixation and embedding, while providing a clean and …
From XenoMouse technology to panitumumab, the first fully
2007年10月5日 · Therapeutic monoclonal antibodies have shown limited efficacy and safety owing to immunogenicity of mouse sequences in humans. Among the approaches developed …
A novel mouse strain optimized for chronic human antibody ...
2022年3月3日 · Here, we present a mouse strain that expresses human IgG1 and FcγRs, thereby conferring tolerance to chronic administration of human IgG and enabling functional …
Human Anti-Mouse Antibody - an overview | ScienceDirect Topics
Human Anti-Mouse Antibody (HAMA) refers to a minimal immune response that occurs in humans after the administration of murine antibodies. HAMA response is reduced in a specific type of …
Human anti-mouse antibody - Wikipedia
Human anti-mouse antibody or human anti-murine antibody (HAMA) is an antibody found in humans which reacts to immunoglobins found in mice. [1] Antibody treatment is a type of …