2020年12月30日 · The Myc-associated zinc finger protein (MAZ) is often found at genomic binding sites adjacent to CTCF, a protein which affects large-scale genome organization through its interaction with cohesin. We show here that, like CTCF, MAZ physically interacts with a cohesin subunit and can arrest cohesin sliding independently of CTCF.

2022年1月30日 · In this review, we aim to offer a comprehensive understanding of MAZ regulation in malignant tumors. The carboxy terminal of MAZ protein contains six C2H2 zinc fingers, and its regulation of transcription is based on the interaction between the GC-rich DNA binding sites of target genes and its carboxy-terminal zinc finger motifs.

2022年1月30日 · 在这篇综述中，我们旨在全面了解恶性肿瘤中的 maz 调控。 MAZ蛋白的羧基末端含有6个C2H2锌指，其转录调控是基于靶基因富含GC的DNA结合位点与其羧基末端锌指基序之间的相互作用。

Myc-associated zinc finger protein is a protein that in humans is encoded by the MAZ gene. [5][6][7] MAZ (gene) has been shown to interact with BPTF [8] and Deleted in Colorectal Cancer. [9] ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. ^ "Mouse PubMed Reference:".

MAZ, a Myc-associated zinc finger protein, is essential for the ME1a1-mediated expression of the c-myc gene during neuroectodermal di•erentiation of P19 cells

2025年3月30日 · MAZ (MYC Associated Zinc Finger Protein) is a Protein Coding gene. Diseases associated with MAZ include Amyloidosis and Spondylocostal Dysostosis 5. Among its related pathways are 16p11.2 proximal deletion syndrome and Sudden infant death syndrome (SIDS) susceptibility pathways.

2021年2月16日 · The Myc-associated zinc finger protein (MAZ) is often found at genomic binding sites adjacent to CTCF, a protein which affects large-scale genome organization through its interaction with cohesin. We show here that, like CTCF, MAZ physically interacts with a cohesin subunit and can arrest cohesin sl …

The Myc-associated zinc finger protein (MAZ) works together with CTCF to control cohesin positioning and genome organization. We have constructed the bichromatic fluorescent reporter driven by SAF/MAZ 5'-proximal promoter plasmids from which transactivation status of SAF-1 and SAF-3 alternative promoter could be monitored by EGFP and DsRed ...

2024年9月24日 · Title: The Myc-associated zinc finger protein (MAZ) works together with CTCF to control cohesin positioning and genome organization. We have constructed the bichromatic fluorescent reporter driven by SAF/MAZ 5'-proximal promoter plasmids from which transactivation status of SAF-1 and SAF-3 alternative promoter could be monitored by EGFP and ...

2024年4月23日 · The MYC-Associated Zinc Finger Protein (MAZ) plays important roles in chromatin organization and gene transcription regulation. Dysregulated expression of MAZ causes diseases, such as glioblastoma, breast cancer, prostate cancer, and liposarcoma. Previously, it has been reported that MAZ controls th …