2011年9月14日 · MALDI-TOF-MS（基质辅助激光解吸电离飞行时间质谱, 英文名Matrix-Assisted Laser Desorption/ Ionization Time of Flight Mass Spectrometry）是近年来发展起来的一种新型的软电离生物质谱，其无论是在理论上还是在设计上都是十分简单和高效的。 仪器主要由两部分组成：基质附助激光解吸电离离子源（MALDI）和飞行时间质量分析器（TOF）。 MALDI的原理是用激光照射样品与基质形成的共结晶薄膜，基质从激光中吸收能量传递给生物分子，而电离过程中 …

The Q-Tof Premier is a hybrid orthogonal acceleration Time-of-Flight (oa-ToF) mass spectrometer that enables automated exact mass measurement of precursor and fragment ions to yield the highest confidence in structural elucidation and databank search results

From routine QC to discovery and characterization, the autoflex® maX MALDI-TOF and TOF/TOF systems offer versatility and reliability for the rapid in-depth analysis of polymers or other challenging sample types.

maldi-tof/tof ms应用举例 肝癌/健康人血清中磷酸化 多肽表达的差异分析

Facile glycosidic cleavages directed mostly at N-acetylglucosamine under low energy CID, as implemented on a quadrupole/time-of-flight (Q/TOF) instrument, often afford multiple losses of the attached antenna resulting in characteristic ions related to the number of antennary branches on the trimannosyl core.

The MALDI Q-Tof Premier provides an efficient switch between API and MALDI modes to deliver the degree of flexibility required in today’s research environment. By simply removing the API source, the MALDI source unit is transferred via a motorized stage to the so urce region, and is fixed in position. MALDI Q-Tof Premier: MALDI source

2014年10月10日 · maldi-tof是一套系统，蛋白分析用的多，优点是质量范围宽，缺点是灵敏度低，重现性差。 Q-TOF是四级杆串联TOF，都是质量分析器，结合使用可以做蛋白的二级分析。

This work also provides first real examples of sequencing multiply sialylated complex type N-glycans by high energy CID on a TOF/TOF instrument. Concerted MALDI-MS profiling and CID MS/MS sequencing of permethylated glycans is one of the most effective approaches for high throughput glycomics applic

2025年3月27日 · 在与MALDI相同的MS平台上，Waters Q-TOF Premier同时提供UPLC/MS/MS功能的选择。 将StepWave和UPLC分离与定量飞行时间(QuanTof)技术相结合，实现最高的峰容量和数据质量。

2010年3月15日 · Whole cell lysates were analyzed using both matrix assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF/MS) and liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF/MS).