2008年11月20日 · MYH9 -related disease (MYH9 -RD) is characterized in all affected individuals by hematologic features present from birth consisting of platelet macrocytosis (i.e., >40% of …

2024年12月25日 · MYH9 (Myosin Heavy Chain 9) is a Protein Coding gene. Diseases associated with MYH9 include Macrothrombocytopenia And Granulocyte Inclusions With Or Without …

MYH9 -related disorder can have many signs and symptoms, including bleeding problems, hearing loss, kidney (renal) disease, and clouding of the lens of the eyes (cataracts). Explore …

2024年2月1日 · MYH9 acts as a tumor promoter in most tumors by activating some classical signaling pathways. The myosin heavy chain 9 (MYH9) gene encodes the heavy chain of non …

MYH9 is a large gene localized on chromosome 22q12.3, spanning more than 106 kbp and composed of 41 exons. The open reading frame, spread from exon 2 to exon 41, encodes a …

May-Hegglin anomaly and Sebastian, Fechtner, and Epstein syndromes belong to MYH9 disorders. The present review summarizes the recent advances in genetic diagnosis and our …

MYH9 is a novel cancer stem cell marker and prognostic indicator in esophageal cancer that promotes oncogenesis through the PI3K/AKT/mTOR axis. Long Noncoding RNA TPRG1-AS1 …

The MYH9 gene provides instructions for making a protein called myosin-9. This protein is one part (subunit) of the myosin IIA protein. There are three forms of myosin II, called myosin IIA, …

Myosin heavy chain 9 (MYH9) encodes a protein called non-muscle myosin II (NMM-II), which belongs to the myosin superfamily. NMM-II is a hexamer composed of 2 heavy chains (220 …

2018年7月20日 · The MYH9 gene encodes the heavy chain of non-muscle myosin IIA, a widely expressed cytoplasmic myosin that participates in a variety of processes requiring the …