MSCs secrete cytokines either “spontaneously” or after induction by other cytokines, the most important being IFNγ, TNFα and IL-1β[62-64], and it should be underlined that MSCs are not …

2018年5月16日 · Mesenchymal stromal cells (MSC) secrete factors that contribute to organ homeostasis and repair in a tissue specific manner.

2023年5月25日 · We have found that umbilical cord-derived MSCs conditioned media demonstrated the highest cytokine and growth factor levels and despite mostly pro …

2009年2月1日 · In this study, we attempted to determine a comprehensive cytokine secretion profile of MSCs with the use of a wide-spectrum human cytokine antibody array. This profile …

Growth factors, cytokines, chemokines, extracellular matrix components, and metabolic products were all found to be functional molecules of MSCs in various therapeutic paradigms. These …

2019年8月8日 · Here, we analyzed the influence of some commonly used cytokines in MSC expansion, such as epidermal growth factor (EGF), basic fibroblast growth factor 2 (FGF2), …

2022年2月1日 · MSC-secreted cytokines can regulate MSC function in both an autocrine and a paracrine manner. For example, the binding of secreted IL-8 to its receptor CXCR1 or CXCR2 …

6 天之前 · Burnham AJ, Foppiani EM, Goss KL, Jang-Milligan F, Kamalakar A, Bradley H, et al. Differential response of mesenchymal stromal cells (MSCs) to type 1 ex vivo cytokine priming: …

2025年3月22日 · Additionally, MSC-secreted MMP14 promotes MSC proliferation and self-renewal, while also inducing cytokine alterations. MSC-derived MMP14 may promote AML …

2025年3月5日 · Moreover, we also examined the circulating inflammatory cytokine levels in tumor bearing mice, the results showed the decreased levels of IL-6, TNF, and IL-12, but increased …