Letrozole works by blocking the action of the enzyme aromatase, which prevents the body from converting androgens into estrogens. Estrogen is a hormone that causes estrogen receptor-positive (ER+) breast cancer to grow.

Letrozole is commonly used to treat certain types of breast cancer, including hormone receptor-positive breast cancer, in women after menopause. Letrozole may also be used for other conditions...

Letrozole is used to treat certain types of breast cancer in women who have already stopped menstruating (postmenopausal). It is also used for women who have already had other cancer treatments (eg, tamoxifen).

LETROZOLE (LET roe zole) treats some types of breast cancer. It works by decreasing the amount of estrogen hormone your body makes, which slows or stops breast cancer cells from spreading or growing.

Letrozole is an orally active, nonsteroidal, selective aromatase inhibitor and hence an antiestrogen. It prevents aromatase from producing estrogens by competitive, reversible binding to the heme of its cytochrome P450 unit. The action is specific, and letrozole does not reduce production of corticosteroids. [citation needed

2024年8月30日 · Letrozole (brand name Femara) is a treatment that may be used to reduce the risk of breast cancer recurrence in postmenopausal women and also to increase the chance of ovulation in women with polycystic ovary syndrome.

2024年7月12日 · Learn about the side effects of letrozole, from common to rare, for consumers and healthcare professionals.