Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD), is an autosomal recessive disorder characterized by a lack of insulin-like growth factor 1 (IGF-1; somatomedin-C) production in response to growth hormone (GH; hGH; somatotropin). [6]

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Laron syndrome is a rare form of short stature that results from the body's inability to use growth hormone , a substance produced by the brain's pituitary gland that helps promote growth. Explore symptoms, inheritance, genetics of this condition.

Laron syndrome is a condition that occurs when the body is unable to utilize growth hormone. It is primarily characterized by short stature. Other signs and symptoms vary but may include reduced muscle strength and endurance; hypoglycemia in infancy; delayed puberty; short limbs (arms and legs); and obesity.

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Laron’s syndrome (LS) is a rare genetic disorder characterized by insensitivity to growth hormone (GH). Up to the present time, over 70 mutations of GH receptor (GHR) gene have been identified leading to GH/insulin-like growth factor type 1 (IGF1) signaling pathway defect.

2024年4月30日 · To find out, Longo and Guevara-Aguirre examined Torres and 23 others with Laron syndrome and compared them with 27 of their first-degree relatives without the condition, most of whom live in...

Laron syndrome (LS) is a rare genetic endocrinopathy that results from mutation of the growth hormone receptor (GH-R) gene and is typically associated with dwarfism and obesity. LS is the best characterized entity under the spectrum of the ...

2022年7月29日 · Laron syndrome, also known as Laron-type dwarfism, is a rare genetic disorder in which there is a deficit of response to growth hormones. People with Laron syndrome have short stature and other physical features, caused by …

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