
乳酸脱氢酶 - 百度百科
乳酸脱氢酶(lactate dehydrogenase,LD或LDH,EC1.1.1.27)是一类NAD依赖性激酶,有LDHA、LDHB、LDHC三种亚基,可构成6种四聚体同工酶。 动物乳酸脱氢酶是由4个亚单位组成的四聚体,常见的A、B两种亚基构成的5种LDH同工酶(LDH1-5),C亚基则仅组成一种LDH同工酶 …
Lactate Dehydrogenase (LDH) Isoenzymes Test - MedlinePlus
What is a lactate dehydrogenase (LDH) isoenzymes test? This test measures lactate dehydrogenase (LDH) isoenzymes in a sample of your blood. It's a general test that can help find out if you have tissue damage from disease or injury. It can also help show which organs and other tissues are likely to be damaged.
Biochemistry, Lactate Dehydrogenase - StatPearls - NCBI Bookshelf
2023年5月1日 · Lactate dehydrogenase (LDH) is an important enzyme of the anaerobic metabolic pathway. It belongs to the class of oxidoreductases, with an enzyme commission number EC 1.1.1.27. The function of the enzyme is to catalyze the reversible conversion of lactate to pyruvate with the reduction of NAD+ to NADH and vice versa. [1] .
认识检查 | 乳酸脱氢酶(LDH)——普通又熟悉的生化指标,你了 …
乳酸脱氢酶(lactatedehydrogenase,LD或LDH)是一类 烟酰胺腺嘌呤二核苷 (NAD)依赖性激酶。 LDH是糖酵解的重要酶系之一,可催化丙酸与L-乳酸之间的还原氧化反应,也可催化相关的α-酮酸。 LDH主要存在于心肌、肝、肾、骨骼肌和肺等组织中。 红细胞内LDH约为正常血清的100倍。 LDH有LDHA、LDHB、LDHC三种亚基,可构成6种四聚体同工酶。 常见的A、B两种亚基构成5种LDH同工酶(LDH1~5),C亚基则仅组成一种LDH同工酶即LDH-C4。
LDH1、LDH2、LDH3的具体含义分别是什么 - 百度知道
人组织中的乳酸脱氢酶(LDH)用电泳法可以分离出5种同工酶区带,根据其电泳迁移率的快慢,依次命名为LDH1,LDH2,LDH3,LDH4,LDH5。 乳酸脱氢酶(lactate dehydrogenase,LDH)几乎存在于所有组织中,以心、骨骼肌和肾脏最丰富,其次为肝、脾、胰腺、脑、肺脏等。
LDH检测实验——原理、步骤、注意事项、示例图 - 知乎
乳酸脱氢酶 (lactatedehydrogenase,LDH)是一种广泛存在于各种生物体中稳定的胞浆酶,正常时不能通过细胞膜,当细胞受损伤或死亡时可释放到细胞外,释放出的LDH 在培养基上清中,可通过偶联酶反应来定量检测。
乳酸脱氢酶(LDH)——研究最为清楚的同工酶 - 搜狐
2018年12月3日 · 两种亚基以不同比例组成五种ldh形式,即ldh1 (由四个心肌型亚基组成)、ldh2 (由三个心肌型亚基和一个骨骼肌型亚基组成)、ldh3(是由两个心肌型亚基和两个骨骼肌型亚基组成)、ldh4 (由一个心肌型亚基和三个骨骼肌型亚基组成)、ldh5(由四个骨骼肌型亚 ...
乳酸脱氢酶 - A+医学百科
同功酶有五种形式,即LDH-1(H4)、LDH-2(H3M)、LDH-3(H2M2)、LDH-4(HM3)及LDH-5(M4),可用电泳方法将其分离。 LDH同功酶的分布有明显的 组织特异性,所以可以根据其组织特异性来协用诊断 疾病。 正常人 血清 中LDH2,〉LDH1。 如有 心肌 酶释放入血则LDH1〉LDH2,利用此指标可以观察诊断心肌疾病。 正常范围:血清 100~300U/L; 尿 560~2050U/L; 脑脊液 含量为血清的1/10。 乳酸脱氢酶是一种 糖酵解酶。 乳酸脱氢酶存 …
CDD Conserved Protein Domain Family: LDH_1 - National …
L-lactate dehydrogenases (LDH) are tetrameric enzymes catalyzing the last step of glycolysis in which pyruvate is converted to L-lactate. This subgroup is composed of eukaryotic LDHs. Vertebrate LDHs are non-allosteric. This is in contrast to some bacterial LDHs that are activated by an allosteric effector such as fructose-1,6-bisphosphate.
Health Encyclopedia - University of Rochester Medical Center
If the blood sample is contaminated by broken red blood cells, a condition called hemolysis, your LDH will be elevated. If you exercise strenuously before the sample is taken, you could have elevated LDH-1, LDH-2, and LDH-5. Anesthetics, aspirin, narcotics, and certain other medicines can elevate your LDH.