生长激素受体（英语： Growth hormone receptor)是一种由人类基因GHR 编码的蛋白质 [1] ，GHR的直系同源物 [2] 广泛存在于各种哺乳动物中。 此基因编码的蛋白是结合 生长激素 的跨膜受体。

There are two main types of growth hormone (GH) in the circulatory system. One is 22 kD-GH, which is the predominant isoform in the circulating system, 90% GH is present as a 22 kD protein, and 10% of GH is present as a 20 kD protein.

Karnatak University was established at Dharwad in the Indian state of Karnataka in October 1949. It had its official inauguration in March 1950. The campus spans 888 acres (3.59 km 2). Dr. D. …

生长激素（growth hormone，GH）是一种由脑垂体前叶嗜酸性细胞分泌的由191个氨基酸组成的单链亲水球蛋白，对机体的生长发育起重要作用。 生长激素受体 ( growth hormone receptor,GHR) 是GH发挥作用的生理基础, GH必须与靶细胞表面的GHR 结合，诱导GHR分子同源二聚化，然后激活细胞内一系列信号传导 [1]。 当体内GH水平低于或等于生理激素浓度时， GH 与GHR 以1：2 相结合。 在超生理激素浓度下,激素饱和了所有的受体分子形成1：1 的复合物,阻止了受体二聚化 …

2021年1月15日 · Growth hormone (GH) actions via initiating cell signalling through the GH receptor (GHR) are important for many physiological processes, in addition to its well-known role in regulating growth. The activation of JAK-STAT signalling by GH is well characterized, however knowledge on GH activation of SRC family kinases (SFKs) is still limited.

2002年7月8日 · In this study, ligand-independent GHR dimerization is demonstrated in the endoplasmic reticulum and at the cell surface by coimmunoprecipitation of an epitope-tagged truncated GHR with wild-type GHR. In addition, evidence is provided that the extracellular domain of the GHR is not required to maintain this interaction.

2008年1月1日 · The growth hormone receptor (GHR) is the key regulator of postnatal growth and has important actions on metabolism, reproductive, gastrointestinal, cardiovascular, hepto-biliary, and renal systems (Lichanska & Waters, in press). GHR is a type I cytokine receptor and has long been known to utilise the JAK (Janus kinase)/STAT (signal transducers ...

垂体中生长激素（GH）的分泌受两种下丘脑肽的控制：GH释放激素 (GHRH)和生长激素释放抑制激素因子 (SRIF)。 GHRH是GH的主要调控因子，促进GH基因的转录和释放；生长抑素通过抑制生长激素对GHRH的生长营养反应来抑制生长激素的分泌。 第三个因素是 胃饥饿素，它对生长激素分泌具有刺激作用，尽管它在生长激素分泌的生理调节中所起的作用存在争议 [4]。 除此之外，影响生长激素分泌的因素还有很多，如年龄、性别、饮食、运动、压力和其他激素。 葡萄糖和 …

这篇综述概述了有关gh作用的分子机制的最新知识。提出的模型是其中gh与两个ghr结合导致ghr的二聚化，与ghr相关的jak2酪氨酸激酶的激活以及jak2和ghr的酪氨酰磷酸化的模型。

Growth hormone (GH) actions via initiating cell signalling through the GH receptor (GHR) is important for many physiological processes, in addition to its well-known role in regulating growth. The activation of JAK-STAT signalling by GH is well characterized, however knowledge on GH activation of SRC family kinases (SFKs) is still limited.