2008年3月13日 · Here, we describe the development of secondary T-cell acute lymphoblastic leukemia (T-ALL) in two adolescent leukemia patients. Therapy-related ALL (t-ALL) was …

1997年6月1日 · The inv (11) (p15q22) is a recurrent chromosomal abnormality associated with de novo and therapy-related myeloid malignancies. Here we report the molecular definition of this …

1997年6月1日 · The inv(11)(p15q22) is a recurrent chromosomal abnormality associated with de novo and therapy-related myeloid malignancies. Here we report the molecular definition of this …

Our case confirms that the inv(11) is a rare chromosomal translocation that is associated with therapy-related or de novo myeloid malignancy and involves NUP98 and DDX10 but not MLL. …

We identified a yeast artificial chromosome (YAC) clone that spanned the inv (11) breakpoints on 11q. From this YAC, we identified a P1 clone, which included the breakpoints in at least three …

2007年6月1日 · Inv (11) (q21q23); KMT2A-MAML2, a Recurrent Genetic Abnormality in T-Cell Therapy-related Acute Lymphoblastic Leukemia. Molecular pathology of thymomas: …

Significance of inv(11)(p15q23) in Diseases Acute Myeloid Leukemia + inv(11)(p15q23) is an inclusion criterion in 87 clinical trials for acute myeloid leukemia, of which 39 are open and 48 …

The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase …

2014年5月15日 · In vast majority of cases with MLL gene rearrangements, only one chromosome 11 or a single MLL allele got involved. We report two very unusual cases of myeloid …

In another family studied by several banding methods in search of chromosomal markers, a pericentric inv(11) (p11q11) was found. It was detectable only by C-banding, the darkly …