In a collaborative NIH funded study led by Prof. Colleen Clancy we use multi-scale modeling approaches to develop in silico predictive safety pharmacology for drugs, affecting functions of cardiac voltage-gated ion channel proteins K V 11.1 (also known as …

Conformational studies of sphingolipids by NMR spectroscopy. II. Sphingomyelin. Is arginine charged in a membrane?

Effect of the Membrane Environment on Pharmacologic Inhibition of hERG K+ Channel Activity. JACC Clin Electrophysiol. 2025 Jan 16. Fiore CM, Quigley K, Vorobyov I, Clancy CE, Harvey RD. PMID: 39895450. Molecular simulations reveal intricate coupling between agonist-bound β-adrenergic receptors and G protein. iScience. 2025 Feb 21; 28 (2):111741.

2020年12月4日 · My research team focuses on using computer modeling and simulation techniques, such as molecular docking and molecular dynamics (MD), to study interactions of drugs and other modulators with membrane proteins of biomedical significance such as ion channels and G protein-coupled receptors (GPCR).

2023年8月23日 · Research in our laboratory focuses on using computer modeling and simulation techniques, such as molecular docking and molecular dynamics, to study interactions of drugs and other small molecules with membrane associated and water soluble proteins of …

Igor VOROBYOV, Assistant Professor | Cited by 12,544 | of University of California, Davis, California (UCD) | Read 107 publications | Contact Igor VOROBYOV

2024年11月22日 · Igor Vorobyov Position Title. Assistant Professor. Department of Physiology and Membrane Biology; [email protected]; Faculty Profile; College of Biological Sciences Graduate Academic Programs 227 Green Hall [email protected] . UC Davis …

Principal Investigator: Igor Vorobyov | ResearchGate, the professional network for scientists

Igor VOROBYOV, Assistant Professor | Cited by 11,056 | of University of California, Davis, California (UCD) | Read 101 publications | Contact Igor VOROBYOV