IFNG, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoan infections. IFNG is an important activator of macrophages …

2025年3月30日 · IFNG (Interferon Gamma) is a Protein Coding gene. Diseases associated with IFNG include Immunodeficiency 69 and Hepatitis C Virus. Among its related pathways are …

2018年6月19日 · IFNγ is a cytokine that is primarily produced by cells of the immune system, including innate-like lymphocyte populations, such as natural killer (NK) cells and innate …

Interferon‐gamma (IFN‐γ) is a cytokine that plays an important role in inducing and modulating an array of immune responses. Cellular responses to IFN‐γ are mediated by its heterodimeric …

2020年6月11日 · Signalling by the IFNγ receptor activates the Janus kinase (JAK)-signal transducer and activator of transcription 1 (STAT1) pathway to induce the expression of …

Interferon-gamma (IFN-gamma) coordinates a diverse array of cellular programs through transcriptional regulation of immunologically relevant genes. This article reviews the current …

2025年2月8日 · Title: Cholesterol promotes IFNG mRNA expression in CD4(+) effector/memory cells by SGK1 activation. IL-17 and IFN-gamma-producing Respiratory Tissue-Resident …

Interferon-gamma (IFNG) is a pleiotropic cytokine that modulates both innate and adaptive immune networks; it is the most potent activator of macrophages and a signature cytokine of …

Interferon-γ (IFN-γ) is a cytokine whose biological activity is conventionally associated with cytostatic/cytotoxic and antitumor mechanisms during cell-mediated adaptive immune …

Crystallographic structure of a 3:2 complex of the IFN-γ receptor alpha chain (IFNGR1) (green, cyan, and green/cyan) and the IFN-γ ligand (red and orange). [1] The interferon-gamma …