Interferon-alpha/beta receptor - Wikipedia
The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human type I IFNs include many …
免疫研究领域热门基因之IFNAR1 - 知乎 - 知乎专栏
干扰素 （interferon, IFN）是一组天然存在的细胞因子，最初是以其干扰细胞病毒复制的能力而得名。 干扰素具有重要的免疫调节、抗病毒、抗血管生成、抗增殖和抗肿瘤活性。 根据不同干 …
IFNAR1 Gene - GeneCards | INAR1 Protein | INAR1 Antibody
2025年3月30日 · IFNAR1 (Interferon Alpha And Beta Receptor Subunit 1) is a Protein Coding gene. Diseases associated with IFNAR1 include Immunodeficiency 106 Viral Infections and …
IFNAR | 干扰素受体 | 抑制剂 | MCE - MCE-生物活性分子大师
The interferon-α/β receptor (IFNAR) is composed of two subunits, IFNAR1 and IFNAR2, encoding transmembrane polypeptides. Type I interferons (IFNs) bind IFNAR receptors and activate …
干扰素：来源、去处、机制与疾病 - 知乎 - 知乎专栏
干扰素γ（IFNγ）是一种二聚体可溶性细胞因子，是II型干扰素的唯一成员。 这种干扰素的存在，在其历史的早期被称为免疫干扰素，被EF Wheelock描述为被植物血凝素刺激的人白细胞的产 …
Regulation of type I interferon responses - Nature
2013年12月23日 · Type I interferon (IFN) responses are regulated by host, pathogen and environmental factors. These factors calibrate the host defences while limiting tissue damage …
IFNAR1 and IFNAR2 play distinct roles in initiating type I ... - PubMed
2021年11月23日 · We suggest that tyrosine phosphorylation on IFNAR2-ICD drives the dissociation of phosphorylated STATs, thus maintaining high signaling flux. Type I interferons …
IFNAR1 - Wikipedia
Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene. [5][6] The protein encoded by this gene is a type I membrane protein that forms one of …
IFNAR1 and IFNAR2 play distinct roles in initiating type I ... - AAAS
2021年11月23日 · Type I interferons form a complex with the receptor subunits IFNAR1 and IFNAR2, which stimulates cross-activation of the tyrosine kinases associated with the receptor …
Interferon Receptor Trafficking and Signaling: Journey to the Cross ...
Like most plasma membrane proteins, type I interferon (IFN) receptor (IFNAR) traffics from the outer surface to the inner compartments of the cell. Long considered as a passive means to …