2005年5月1日 · There are two main classes of interferon (IFN): type I IFNs and type II IFN. There are many type I IFNs, including IFN-α, IFN-β and IFN-ω, and all of these bind a common cell …

2015年1月23日 · Type I interferons (IFNs) have diverse effects on innate and adaptive immune cells during infection with viruses, bacteria, parasites and fungi, directly and/or indirectly …

2013年12月23日 · Type I interferon (IFN) responses are regulated by host, pathogen and environmental factors. These factors calibrate the host defences while limiting tissue damage …

Type I IFNs elicit antiviral, antiproliferative and immunomodulatory responses by binding to the type I interferon receptor. The receptor consists of the IFNAR1 and IFNAR2 transmembrane …

Type I interferons (IFN-I) were first described over 50 years ago as factors produced by cells that interfere with virus replication and promote an antiviral state. Innate and adaptive immune …

In this review, we summarize the complicated, but important, role of type I IFNs in influenza infections. This includes both protective and harmful effects of these important cytokines …

2025年1月26日 · Interferons (IFN) are released by host cells in response to invasion by pathogens. Depending on the specific receptor type, human interferons can be categorized …

2025年3月30日 · IFN1@ (Interferon, Type 1, Cluster) is a Gene Cluster. Diseases associated with IFN1@ include Retinal Vasculitis and Rabies. Among its related pathways are Cytokines and …

2024年5月7日 · Type I interferons (IFN-I) represent a group of pleiotropic cytokines renowned for their antiviral activity and immune regulatory functions. A multitude of studies have unveiled a …

Citation 4 IFN-β is the high-affinity short-lived priming IFN and the major IFN-I produced by fibroblasts. Citation 5 IFN-II is mainly secreted by T lymphocytes, natural killer cells (NKs), and …