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Interferons (IFNs, / ˌ ɪ n t ər ˈ f ɪər ɒ n / IN-tər-FEER-on [1]) are a group of signaling proteins [2] made and released by host cells in response to the presence of several viruses. In a typical …

May 1, 2005 · There are two main classes of interferon (IFN): type I IFNs and type II IFN. There are many type I IFNs, including IFN-α, IFN-β and IFN-ω, and all of these bind a common cell …

The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses.

The interferons (IFN)s are a family of cytokines with antiviral, antiproliferative, and antitumor activities, as well as immunomodulatory effects on the innate and adaptive immune responses …

Induction of interferon (IFN) gene expression leads to increase cellular resistance to viral infection and may also affect cell growth. Two subtypes of interferons comprise the IFN family of …

Jun 19, 2018 · IFNγ is a cytokine that is primarily produced by cells of the immune system, including innate-like lymphocyte populations, such as natural killer (NK) cells and innate …

Interferons are the frontline defenders in your body. A variety of cells, including white blood cells, produce interferons in response to infection and other stimuli, like cancer cells. They initiate …

IFNG, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoan infections. IFNG is an important activator of macrophages …

Dec 23, 2013 · Type I interferons (IFNs) are polypeptides that are secreted by infected cells and have three major functions. First, they induce cell-intrinsic antimicrobial states in infected and...

Interferon (IFN) proteins are a family of cytokines secreted by host cells to modulate the immune response. As the first class of cytokines discovered, they were named “interferon” due to the …

Jun 1, 2023 · Interferon-gamma (IFN-γ) is a pleiotropic cytokine that plays a critical role in mediating an array of immune responses including promotes antiviral activity, facilitates …

This article reviews the current understanding of IFN-gamma ligand, receptor, signal transduction, and cellular effects with a focus on macrophage responses and to a lesser extent, responses …

May 30, 2018 · A key player in driving cellular immunity, IFN-γ is capable of orchestrating numerous protective functions to heighten immune responses in infections and cancers. It can …

Jan 23, 2015 · Type I interferons (IFNs) have diverse effects on innate and adaptive immune cells during infection with viruses, bacteria, parasites and fungi, directly and/or indirectly through the...

Jul 10, 2023 · Interferons (IFNs) are proteins that belong to the group of signaling molecules known as cytokines involved in the upregulation of the immune response.

Interferon-gamma (IFN-γ) is a pleiotropic cytokine that plays a critical role in mediating an array of immune responses including promotes antiviral activity, facilitates macrophage activation, …

Sep 1, 2002 · Interferons (IFNs) — the body's first line of antiviral defence — are cytokines that are secreted by host cells in response to virus infection. By inducing the expression of …

Nov 23, 2024 · Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. IFNs belong to the …

Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene. [3][4] Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon (IFN-gamma; MIM …