
Targeting photodynamic and photothermal therapy to the …
2019年7月26日 · Immunogenic cell death (ICD)-associated immunogenicity can be evoked through reactive oxygen species (ROS) produced via endoplasmic reticulum (ER) stress. In this study, we generate a double...
Nano Res.│东南大学顾宁课题组:吲哚菁绿组装自由纳米氧气泡增 …
2022年4月22日 · 吲哚菁绿(Indocyanine Green,ICG)是唯一获得美国FDA批准可用于临床的近红外(near infra-red,NIR)荧光染料。在NIR光照下,ICG能产生ROS或 1 O 2 用于PDT。然而,ICG自身存在的一些不足,如分子容易聚集、 1 O 2 量子产率低和水溶液稳定性差等,限制了其临床应用。同时 ...
Medical Applications and Advancement of Near Infrared …
2023年8月16日 · Indocyanine green (ICG) is an important kind of near infrared (NIR) photosensitive molecules for PTT/PDT therapy as well as imaging. When exposed to NIR light, ICG can produce reactive oxygen species (ROS), which can kill …
Indocyanine green assembled free oxygen-nanobubbles towards …
2022年1月29日 · Photodynamic therapy (PDT) has shown a promising capability for cancer treatment with minimal side effects. Indocyanine green (ICG), the only clinically approved near-infrared (NIR) fluorophore, has been used as a photosensitizer for PDT in clinical application.
吲哚菁绿组装游离氧纳米气泡以增强近红外诱导光动力疗法 …
2022年1月29日 · 吲哚菁绿 (ICG) 是唯一经临床批准的近红外 (NIR) 荧光团,已在临床应用中用作 PDT 的光敏剂。 然而,临床上直接利用ICG的主要障碍在于其单线态氧(1O2)量子产率(QY)低和在水溶液中的不稳定性。 为了提高 ICG 的 PDT 功效,将游离 ICG 分子与游离氧纳米气泡 (NBs-O2) 组装在一起,通过气-液界面上的亲水-疏水相互作用制备 ICG-NBs-O2。 有趣的是,ICG-NBs-O2 溶液的 1O2 QY 显着提高到 1.6%,估计是游离 ICG 溶液的 8 倍。 同时,与游 …
ICG/l-Arginine Encapsulated PLGA Nanoparticle-Thermosensitive …
2021年1月11日 · Photodynamic therapy (PDT) is promising for clinical cancer therapy; however, the efficacy was limited as an individual treatment regimen. Here, an approach synergistically combining PDT and nitric oxide (NO) gas therapy along with destruction of the tumor extracellular matrix (ECM) was presented to eliminate cancer.
Strategies to improve photodynamic therapy efficacy by relieving …
2021年4月30日 · Photodynamic therapy (PDT) is an emerging technology for tumor treatment in which photosensitizer (PS)-mediated light irradiation reduces oxygen, producing high levels of reactive...
Near-infrared photothermal/photodynamic therapy with
2017年10月24日 · Indocyanine green (ICG) is a photothermal agent, photosensitizer, and fluorescence imaging probe which shows specific accumulation in hepatocellular carcinoma (HCC) cells. We recently...
吲哚菁绿组装自由纳米氧气泡增强近红外诱导的光动力治疗-东南大 …
2021年12月27日 · 吲哚菁绿(Indocyanine Green,ICG)是唯一获得临床批准的近红外荧光团,在临床应用中已被用作PDT的光敏剂。 为提高ICG的PDT疗效,将自由ICG分子在自由纳米氧气泡(NBs-O 2 )的气液界面上自组装,通过亲疏水作用制备得到ICG-NBs-O 2 水溶液。
Photodiagnosis Photodyn Ther:吲哚青绿介导的光动力疗法治疗糖尿病患者种植体周围炎的临床、细菌和炎症结果 …
近日,发表于Photodiagnosis Photodyn Ther的一项为期6个月的随机对照临床试验评估了吲哚青绿介导的光动力疗法(ICG-PDT)作为种植体周围人工清创术(PIMD)的辅助手段VS