Myocardial scarring is the accumulation of fibrous tissue resulting after some form of trauma to the cardiac tissue. [1][2] Fibrosis is the formation of excess tissue in replacement of necrotic or extensively damaged tissue.

In this article, we outline the scar formation process following an MI, discuss interpretation of standard measures of heart function in the setting of a healing infarct, then present implications of infarct scar geometry and structure for both mechanical and electrical function of the heart and summarize experiences to date with therapeutic ...

2023年8月21日 · Acute myocardial infarction (MI) causes inflammation and scarring (fibrosis) in response to cardiac muscle cell death. While these processes promote healing of the damaged part of the heart muscle, there is a natural overreaction that causes scarring in …

Cardiac scars, often perceived as “dead” tissue, are very much alive, with heterocellular activity ensuring the maintenance of structural and mechanical integrity following heart injury. To form a scar, non-myocytes such as fibroblasts, proliferate and are recruited from intra- …

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