2020年12月1日 · Preclinical model systems that mimic HPV infections are essential tools for investigations on viral etiology and pathophysiological processes of human diseases. Herein, …

2015年10月12日 · Human papillomaviruses (HPVs) cause a range of serious diseases, including the vast majority of cervical cancers, most anal cancers and around half of head and neck …

2024年11月22日 · We develop a deterministic mathematical model to investigate the transmission dynamics of human papillomavirus (HPV) and its impact on cervical cancer.

2024年7月5日 · Here, we introduce the Human papillomavirus simulator (HPVsim), a new open-source software package for creating flexible agent-based models parameterised with country …

2017年5月2日 · HPVs are double-stranded DNA viruses and can be recognized by PRRs, namely Toll-like receptors (TLR). Among this family of PRRs, TLR-9 is present in the membrane of …

2020年5月12日 · In this paper, we describe an infection-based HNSCC model, utilizing a mouse papillomavirus (MmuPV1), which naturally infects laboratory mice. Infections of the tongue …

2023年6月12日 · In this study, we have developed two animal models, with a genetic design that is easily transposable to different antigens, to validate the efficacy of candidate vaccines. Our …

2014年10月12日 · The cervicovaginal challenge infection model with HPV PsV can induce long-lived tissue resident memory CD8 T cells located in the cervicovaginal epithelium. Therefore, …

2017年5月2日 · For decades, research on the pathogenesis of papillomavirus-induced lesions, particularly of human papillomavirus (HPV) has relied on the use of animal models. Among …

Using this mathematical model we evaluated the impact of human papillomavirus (HPV) on a given population and determined what could decrease the rate at which AAW become …