GPR17 - Wikipedia
GPR17 is a G protein coupled receptor that acts primarily through G proteins linked to the Gi alpha subunit but also to Gq alpha subunit. [7][11] Matching these structural relationships, …
The GPR17 Receptor—A Promising Goal for Therapy and a …
GPR17 receptors are considered to be sensors of local damage to the myelin sheath, and play a role in the reconstruction and repair of demyelinating plaques caused by ongoing inflammatory …
Neuron | GPR17和小胶质细胞的联合操控可诱导再生轴突髓鞘形成 …
该研究成果已于2020年10月26日以 Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia 为题发表于 Neuron。 由于OPCs参与成人的 …
The G Protein-Coupled Receptor GPR17: Overview and Update
2016年12月6日 · The GPR17 receptor is a G protein-coupled receptor (GPCR) that seems to respond to two unrelated families of endogenous ligands: nucleotide sugars (UDP, UDP …
G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte
2018年3月14日 · Here, we demonstrate that the absence of Gpr17 enhances remyelination in vivo with a toxin-induced model whereby focal demyelinated lesions are generated in spinal cord …
The GPR17 Receptor-A Promising Goal for Therapy and a
2020年3月8日 · GPR17 receptors are considered to be sensors of local damage to the myelin sheath, and play a role in the reconstruction and repair of demyelinating plaques caused by …
GPR17: Molecular modeling and dynamics studies of the 3-D …
2008年6月4日 · GPR17 is a G-protein-coupled receptor located at intermediate phylogenetic position between two distinct receptor families: the P2Y and CysLT receptors for extracellular …
GPR17 Gene - GeneCards | GPR17 Protein | GPR17 Antibody
2025年3月30日 · GPR17 (G Protein-Coupled Receptor 17) is a Protein Coding gene. Diseases associated with GPR17 include Periventricular Leukomalacia and Encephalomalacia. Among …
G-protein-coupled receptor GPR17 inhibits glioma development …
2021年6月12日 · Data mining with human LGG and GBM samples reveals that GPR17 is negatively correlated with glioma development. Overexpressing GPR17 inhibits glioma cell …
新型半胱氨酰白三烯/尿嘧啶核苷酸受体GPR17通过调节小胶质细 …
GPR17是受半胱氨酰白三烯CysLTs及尿嘧啶核苷酸UDP双重调节的G蛋白偶联受体。 有报道表明GPR17是脑缺血损伤的一个损伤感受器。 脑缺血后的神经功能损伤，可由缺血直接引起也可 …