Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is the …

2023年5月1日 · GLUT4 is part of a family of glucose transporter proteins containing 12-transmembrane domains. It is expressed primarily in skeletal muscle and adipose tissue. …

Glucose is transported into cardiac myocytes through GLUTs. GLUT4 represents around 70% of the total glucose transport activities. GLUT4 protein expression can be found as early as 21 …

Skeletal muscle both stores glucose as glycogen and oxidizes it to produce energy following the transport step. The principal glucose transporter protein that mediates this uptake is GLUT4, …

GLUT4 is an insulin-regulated glucose transporter that is responsible for insulin-regulated glucose uptake into fat and muscle cells. In the absence of insulin, GLUT4 is mainly found in …

The principal glucose transporter protein that mediates this uptake is GLUT4, which plays a key role in regulating whole body glucose homeostasis. This review focuses on recent advances …

GLUT4 is the main glucose transporter activated by insulin in skeletal muscle cells and adipocytes. GLUT4 storage vesicles (GSVs) traffic in endocytic and exocytic compartments.

GLUT4 controls glucose transport into fat and muscle tissues in response to insulin and also into muscle during exercise. Thus, investigation of regulated GLUT4 trafficking provides a major …

GLUT4 is the primary glucose transporter responsible for insulin-stimulated glucose uptake in skeletal muscle and adipose tissue. Insulin binding to its receptor triggers the translocation of …

The glucose transporter GLUT4 is dynamically sorted and retained intracellularly and redistributes to the plasma membrane (PM) by insulin-regulated vesicular traffic, or ‘GLUT4 translocation’. …