1996年8月1日 · The epitope Fy6 recognized by two monoclonal antibodies (i3A and BG6), which inhibit binding of chemokines to the Duffy antigen, was characterized by means of peptides synthesized on pins (Epitope Scanning Kit) and deletion mutagenesis. Both antibodies showed very similar specificities.

2022年10月27日 · In these PTA NPs, FY6-NPs display NIR-II emission extended to 1400 nm with the highest NIR-II QY (4.2%) and PCE (80%). These features make FY6-NPs perform well in high-resolution imaging of vasculature and NIR-II imaging-guided photothermal therapy (PTT) of …

1987年9月1日 · A new Duffy specificity, Fy6, defined by a murine monoclonal antibody of the IgG1 kappa class, is related to susceptibility to malarial invasion. In humans, Fy6 is present on the red cells of all persons except those of the Fy (a-b-) type, a distribution resembling that of Fy3.

1998年9月15日 · The Duffy (FY) blood group antigens are carried by the DARC glycoprotein, a widely expressed chemokine receptor. The molecular basis of the Fy a /Fy b and Fy(a-b-) polymorphisms has been clarified, but little is known about the Fy x antigen and the FY*X allele associated with weak expression of Fy b, Fy3, Fy5, and Fy6 antigens.

The epitope Fy6 recognized by two monoclonal antibodies (i3A and BG6), which inhibit binding of chemokines to the Duffy antigen, was characterized by means of peptides synthesized on pins (Epitope Scanning Kit) and deletion mutagenesis. Both …

1989年8月15日 · A murine monoclonal antibody, named anti-Fy6, which agglutinates all human red cells except those of Fy(a-b) phenotype was used for purification and characterization of Duffy antigens.

2002年5月21日 · Fy(a-b-) phenotype; Fy3, Fy5, Fy6, and Fy4 antigens. Duffy genotype determination. Site density, development, and distribution of Duffy antigens. The Duffy glycoprotein is a chemokine receptor. Duffy antigens and malaria

Two further antigens (Fy5 and Fy6) exist within the system, but are rarely chanced upon. The prevalence of the antigens in Caucasian, Black and Chinese populations is detailed below. There is also the further complication of Fy mod (Fyx) antigen, which is a weakened form of the Fyb antigen – and which is, therefore, not detected by all available

1996年8月1日 · The epitope Fy6 recognized by two monoclonal antibodies (i3A and BG6), which inhibit binding of chemokines to the Duffy antigen, was characterized by means of peptides synthesized on pins (Epitope Scanning Kit) and deletion mutagenesis.

2023年12月2日 · Duffy 血型系统是继ABO血型之后第8个被发现的血型系统。 Duffy抗原是位于细胞膜表面的糖蛋白，其成熟蛋白是α螺旋7次跨膜,N端在细胞外,C端在细胞内,属于G蛋白偶联家族，其相对分子质量为35 000~50000，是一种趋化因子受体，基因位于1号染色体上，该血型系统主要包含Fya、Fyb、Fy3、Fy4、 Fy5、Fy6，这6种抗原。 在人群中产生的表现型主要有Fy (a+b+)、Fy (a+b-)、Fy (a-b+)、Fy (a-b-)。 Duffy 血型系统抗体大多数由于输血而产生，天然产生的情况 …