FANCD2 - Wikipedia
Mono-ubiquination of FANCD2 is essential for repairing DNA interstrand crosslinks, and clamps the protein on DNA together with its partner protein FANCI. The monoubiquitinated …
FANCD2 Gene - GeneCards | FACD2 Protein | FACD2 Antibody
2025年3月30日 · FANCD2 (FA Complementation Group D2) is a Protein Coding gene. Diseases associated with FANCD2 include Fanconi Anemia, Complementation Group D2 and Fanconi …
FA 互补组 D2（FANCD2）基因 | MCE - MCE-生物活性分子大师
范可尼贫血是一种遗传异质性隐性疾病，其特征是细胞遗传学不稳定、对 DNA 交联剂过敏、染色体断裂增加和 DNA 修复缺陷。 Fanconi 贫血互补组的成员不具有序列相似性；它们通过组装 …
FANCD2–FANCI surveys DNA and recognizes double- to single …
2024年7月31日 · FANCD2–FANCI is a sliding clamp that diffuses on double-stranded DNA but stalls when it reaches a single-stranded gap, providing a unified molecular mechanism that …
The FANCI/FANCD2 complex links DNA damage response to R
2024年1月23日 · While the Fanconi anemia pathway has a well-characterized function in DNA crosslink repair, its newly uncovered role in regulating R-loop metabolism has not been fully …
ATR介导的FANCI磷酸化同时调控FANCD2的泛素化和去泛素化 - 知乎
FANCD2的单泛素化在时间和空间上受FA核心复合物（E3环连接酶）、USP1:UAF1（去泛素化酶）和ATR激酶的调控。 FANCI是FANCD2的 异源二聚体，在这一调控中起着重要作用。 特别 …
FANCD2 FA complementation group D2 [ (human)] - National …
FANCD2 inhibits ferroptosis by regulating the JAK2/STAT3 pathway in osteosarcoma. FANCD2 promotes mitotic rescue from transcription-mediated replication stress in SETX-deficient …
FANCD2 and DNA Damage - MDPI
2017年8月19日 · Among those studies, FA group D2 protein (FANCD2) has emerged as the focal point of FA signaling and plays crucial roles in multiple aspects of cellular life, especially in the …
FANCD2的作用机制及其在肿瘤中的研究进展 - 中国医师杂志
FANCD2是FA基因家族中的一员，已成为FA信号传导的焦点。研究发现，FANCD2在肿瘤的发生发展中发挥重要作用并能够作为铁死亡(ferroptosis)的相关基因参与调节铁死亡。
FANCD2 and DNA Damage - PubMed
2017年8月19日 · Among those studies, FA group D2 protein (FANCD2) has emerged as the focal point of FA signaling and plays crucial roles in multiple aspects of cellular life, especially in the …