Dopamine receptor D 2, also known as D 2 R, is a protein that, in humans, is encoded by the DRD2 gene.

2017年7月13日 · What is DRD2? The dopamine D2 receptor, encoded by the DRD2 gene, plays a critical role in response to antipsychotic medications. All antipsychotic medications bind to the D2 receptor, underscoring its importance in treating psychotic symptoms.

2024年12月24日 · DRD2 (Dopamine Receptor D2) is a Protein Coding gene. Diseases associated with DRD2 include Dystonia 11, Myoclonic and Major Depressive Disorder. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and Monoamine GPCRs.

Although less intensively studied than substance use disorders, the DRD2 gene has been implicated in Tourette's syndrome (TS), post-traumatic stress disorder (PTSD) and certain symptoms associated with affective disorders and schizophrenia.

Gene ID: 1813, updated on 8-Feb-2025. This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have …

2020年6月11日 · DRD2 is activated by the endogenous neurotransmitter dopamine and synthetic agonist drugs such as bromocriptine 3, leading to stimulation of G i and inhibition of adenylyl cyclase. Here we used...

2025年2月8日 · Title: DRD2 activation inhibits choroidal neovascularization in patients with Parkinson's disease and age-related macular degeneration. Receptor density influences ligand-induced dopamine D2L receptor homodimerization.