The Role of CTNNA1 in Malignancies: An Updated Review
Catenin alpha 1 (CTNNA1), encoding α-catenin, is involved in several physiological activities, such as adherens junction synthesis and signal transduction. Recent studies have suggested …
CTNNA1 Gene - GeneCards | CTNA1 Protein | CTNA1 Antibody
2025年3月28日 · CTNNA1 (Catenin Alpha 1) is a Protein Coding gene. Diseases associated with CTNNA1 include Macular Dystrophy, Patterned, 2 and Diffuse Gastric And Lobular Breast …
Cancer predisposition and germline CTNNA1 variants
CTNNA1, encoding for α-E-catenin, and E-cadherin-partner in the adherens junction complex, has been recently classified as a HDGC predisposing gene. Nevertheless, little is known about …
连环蛋白α1（CTNNA1）基因 | MCE
该基因编码连环蛋白家族的一个成员，该蛋白通过将位于质膜上的钙粘蛋白连接到细胞内的肌动蛋白丝，在细胞粘附过程中发挥重要作用。 编码的机械传感蛋白包含三个纽蛋白同源结构域， …
CTNNA1 在恶性肿瘤中的作用：最新综述,Journal of Cancer - X-MOL
本综述系统总结了CTNNA1在不同肿瘤中的不同功能，并简要描述了不同类型肿瘤中涉及的不同通路和机制。 CTNNA1在白血病和消化系统、泌尿生殖系统、乳腺癌等实体瘤中异常表达，与 …
CTNNA1 catenin alpha 1 [ (human)] - National Center for …
A germline truncating allele of alpha-E-catenin (CTNNA1) was identified that was present in two family members with invasive diffuse gastric cancer and four in which intramucosal signet ring …
CTNNA1 , a New HDGC Gene: Inactivating Mechanisms and …
2023年3月17日 · This chapter focuses on CTNNA1, the second gene to be acknowledged as a hereditary diffuse gastric cancer (HDGC) predisposing gene. CTNNA1 loss of function was …
Loss-of-function variants in CTNNA1 detected on multigene
2020年2月13日 · Herein, we provide the first large-scale report of CTNNA1 sequencing findings on MGPT through a commercial lab. The data reveal multiple new CTNNA1 LOF variants, …
CTNNA1 catenin alpha 1 [Homo sapiens (human)] - Gene - NCBI
2024年11月27日 · Gene target information for CTNNA1 - catenin alpha 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
Entry - *116805 - CATENIN, ALPHA-1; CTNNA1 - OMIM
2016年4月8日 · HGNC Approved Gene Symbol: CTNNA1. Cytogenetic location: 5q31.2 Genomic coordinates (GRCh38) : 5:138,753,425-138,935,034 (from NCBI) E-cadherin is a …