Cohesin is a protein complex that mediates sister chromatid cohesion, homologous recombination, and DNA looping. Cohesin is formed of SMC3, SMC1, SCC1 and SCC3 (SA1 …

Cohesin is particularly important in meiotic cells to hold bivalents together during homologous recombination and DSB repair. Whether cohesin is actively recruited to sites of DSBs during …

The functions of cohesin are regulated by phosphorylation, acetylation, ATP hydrolysis, and site-specific proteolysis. Recent evidence suggests that cohesin acts as a novel topological device …

2021年3月22日 · Beyond its originally discovered role tethering replicated sister chromatids, cohesin has emerged as a master regulator of gene expression. Recent advances in …

2008年11月15日 · Cohesin is a chromosome-associated multisubunit protein complex that is highly conserved in eukaryotes and has close homologs in bacteria. Cohesin mediates …

Cohesin is a ring-shaped protein complex that organises the genome, enabling its condensation, expression, repair and transmission. Cohesin is best known for its role in chromosome …

Cohesin and condensin share some structural similarities, but they also have distinct subunit compositions. Cohesin is composed of four core subunits: SMC1A, SMC3, RAD21, and …

The functions of cohesin are regulated by phosphorylation, acetylation, ATP hydrolysis, and site-specific proteolysis. Recent evidence suggests that cohesin acts as a novel topological device …

Cohesin regulates expression of genes that control differentiation, morphogenesis, proliferation, and pluripotency. The cohesin complex consists of the Smc1, Smc3, Rad21 and Stromalin …

2012年8月1日 · This pairing function between the duplicated genome is primarily provided by a multimeric protein complex, called cohesin. Thus, genome integrity largely depends on …